Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0035 | - |
GTP | pH 7.1, 30°C | Homo sapiens | |
0.0076 | - |
5-hydroxy-L-lysine | cosubstrate GTP, pH 7.1, 30°C | Homo sapiens | |
0.28 | - |
5-hydroxy-L-lysine | cosubstrate ATP, pH 7.1, 30°C | Homo sapiens | |
0.81 | - |
ATP | pH 7.1, 30°C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | A2RU49 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-hydroxy-L-lysine | catalytic efficiency is 22fold higher with GTP than with ATP | Homo sapiens | ADP + O-phosphohydroxy-L-lysine | - |
? | |
GTP + 5-hydroxy-D-lysine | best substrate is the physiological form 5-hydroxy-L-lysine but human enzyme can also phosphorylate at a lower rate at least one other isomer | Homo sapiens | GDP + O-phosphohydroxy-D-lysine | - |
? | |
GTP + 5-hydroxy-L-lysine | best substrate is the physiological form 5-hydroxy-L-lysine but human enzyme can also phosphorylate at a lower rate at least one other isomer | Homo sapiens | GDP + O-phosphohydroxy-L-lysine | - |
? | |
additional information | no substrates for phosphorylation: ethanolamine, hydroxyproline, homoserine, serine, or choline | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AGPHD1 | - |
Homo sapiens |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
5 | - |
ATP | pH 7.1, 30°C | Homo sapiens | |
12 | - |
5-hydroxy-L-lysine | cosubstrate ATP, pH 7.1, 30°C | Homo sapiens | |
45 | - |
5-hydroxy-L-lysine | cosubstrate GTP, pH 7.1, 30°C | Homo sapiens | |
110 | - |
GTP | pH 7.1, 30°C | Homo sapiens |