Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NTP + 2',2'-difluorodeoxycytidine | Homo sapiens | i.e. gemcitabine, rate limiting enzyme in the activation of the pharmaceutically relevant substrate which is commonly used in the treatment of solid malignant tumors | NDP + 2',2'-difluorodeoxycytidine 5'-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
patients suffering from pancreatic cancer, survival of patients is found to be correlated to the detected enzyme level | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
AsPC-1 cell | - |
Homo sapiens | - |
BxPC3 cell | - |
Homo sapiens | - |
CAPAN-1 cell | - |
Homo sapiens | - |
CAPAN-2 cell | - |
Homo sapiens | - |
CFPAC cell | - |
Homo sapiens | - |
HS578 cell | - |
Homo sapiens | - |
HS766T cell | - |
Homo sapiens | - |
MiaPaCa-2 cell | - |
Homo sapiens | - |
PANC-1 cell | - |
Homo sapiens | - |
pancreas | pancreatic cancer tissue, enzyme detected in 40 out of 44 patient samples | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NTP + 2',2'-difluorodeoxycytidine | i.e. gemcitabine, rate limiting enzyme in the activation of the pharmaceutically relevant substrate which is commonly used in the treatment of solid malignant tumors | Homo sapiens | NDP + 2',2'-difluorodeoxycytidine 5'-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dCK | - |
Homo sapiens |