Literature summary for 2.7.1.74 extracted from

Csapo, Z.; Sasvari-Szekely, M.; Spasokoukotskaja, T.; Talianidis, I.; Eriksson, S.; Staub, M.
Activation of deoxycytidine kinase by inhibition of DNA synthesis in human lymphocytes (2001), Biochem. Pharmacol., 61, 191-197.

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Activating Compound

Activating Compound	Comment	Organism	Structure
aphidicolin	at 0.006-0.012 mM, 2-3fold activation	Homo sapiens

Application

Application	Comment	Organism
medicine	direct inhibition of DNA polymerases by aphidicolin stimulated enzyme in normal, acute myeloid leukaemic and HL60 promyelocytic cells	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	inactivation of purified enzyme by protein phosphatases	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
lymphocyte	normal, acute myeloid leukemic and HL60 promyelocytic cells	Homo sapiens	-

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Release 2023.1 (January 2023)