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Literature summary for 2.7.1.73 extracted from

  • Kawasaki, H.; Shimaoka, M.; Usuda, Y.; Utagawa, T.
    End-product regulation and kinetic mechanism of guanosine-inosine kinase from Escherichia coli (2000), Biosci. Biotechnol. Biochem., 64, 972-979.
    View publication on PubMed
Search for more literature for 2.7.1.73

Inhibitors

Inhibitors Comment Organism Structure
GDP
-
 Escherichia coli
GTP
-
 Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
 2 * 45000 Escherichia coli
85000
-
-
 Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Reaction

Reaction Comment Organism Reaction ID
ATP + inosine = ADP + IMP ordered bi bi mechanism in which guanosine is the first substrate to bind and GMP is the last product to be released Escherichia coli
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + deoxyguanosine
-
 Escherichia coli ADP + dGMP
-
 ?
ATP + inosine
-
 Escherichia coli ADP + 5'-IMP
-
 ?
ATP + xanthosine
-
 Escherichia coli ADP + XMP
-
 ?
CTP + inosine
-
 Escherichia coli CDP + IMP
-
 ?
dATP + inosine
-
 Escherichia coli dADP + IMP
-
 ?
UTP + inosine
-
 Escherichia coli UDP + IMP
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 45000 Escherichia coli

pI Value

Organism Comment pI Value Maximum pI Value
Escherichia coli isoelectric focusing
-
 6