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Literature summary for 2.7.1.73 extracted from
- Formation of inosine-5-monophosphate by a kinase in cell-free extracts of Ehrlich ascites cells in vitro (1968), Proc. Soc. Exp. Biol. Med., 127, 432-440.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required, optimal concentration: 5 mM | Mus musculus |  |
| Mn2+ | can partially replace Mg2+ in activation | Mus musculus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.078 | - |
Inosine | - |
Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Ehrlich ascites carcinoma cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + inosine | - |
Mus musculus | ADP + 5'-IMP | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
rapid loss of activity | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
- |
Mus musculus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | 8.2 | pH 6.5: about 60% of maximal activity, pH 8.2: about 70% of maximal activity, Tris-maleate buffer | Mus musculus |
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Release 2023.1 (January 2023)
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