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Literature summary for 2.7.1.68 extracted from

  • Porciello, N.; Kunkl, M.; Viola, A.; Tuosto, L.
    Phosphatidylinositol 4-phosphate 5-kinases in the regulation of T cell activation (2016), Front. Immunol., 7, 186.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.68

Activating Compound

Activating Compound Comment Organism Structure
phosphatidic acid
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Homo sapiens 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate Homo sapiens
-
 ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
T-cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 Homo sapiens ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Synonyms

Synonyms Comment Organism
phosphatidylinositol 4,5-biphosphate kinase
-
 Homo sapiens
PIP5Kalpha isoform Homo sapiens
PIP5Kbeta isoform Homo sapiens
PIP5Kgamma isoform Homo sapiens

General Information

General Information Comment Organism
physiological function T lymphocyte triggering is finely tuned by phosphatidylinositol 4,5-biphosphate kinases activity Homo sapiens