Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Triton X-100 | the optimal activity obtained in Triton X-100 is 6fold higher than that obtained in the absence of Triton X-100 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | half-maximal inhibition at a ratio of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1-phosphatidyl-1D-myo-inositol 4-phosphate of 1.5:1 | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
ATP | pH 7.4, 23-25°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | associated with, peripheral membrane protein | Homo sapiens | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | Km: 2 mM, Mg2+ is three times more effective than Mn2+ | Homo sapiens | |
Mn2+ | Km: 0.2 mM, Mg2+ is three times more effective than Mn2+ | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
53000 | - |
x * 53000, SDS-PAGE | Homo sapiens |
150000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.117 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-70°C, stable in concentrated form | Homo sapiens |
4°C, storage causes the 53000 Da enzyme to be slowly degraded to a 45000 Da peptide | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
Homo sapiens | ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 53000, SDS-PAGE | Homo sapiens |