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Literature summary for 2.7.1.67 extracted from

  • Salazar, G.; Craige, B.; Wainer, B.H.; Guo, J.; De Camilli, P.; Faundez, V.
    Phosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesicles (2005), Mol. Biol. Cell, 16, 3692-3704.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
AP-3 adaptor complex phosphatidylinositol-4-kinase type II alpha is a component of Mus musculus 30123
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extrinsic to membrane PI4KIIalpha normally present both in perinuclear and peripheral organelles is substantially decreased in the peripheral membranes of AP-3-deficient mocha fibroblasts Mus musculus
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol Mus musculus PI4KIIalpha regulates membrane recruitment and sorting function of AP-3 complexes ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
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?

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
fibroblast PI4KIIalpha normally present both in perinuclear and peripheral organelles is substantially decreased in the peripheral membranes of AP-3-deficient mocha fibroblasts Mus musculus
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hippocampal mossy fiber PI4KIIalpha is strongly reduced in the nerve terminals of mocha hippocampal mossy fibers Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol
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Mus musculus ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
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?
ATP + 1-phosphatidyl-1D-myo-inositol PI4KIIalpha regulates membrane recruitment and sorting function of AP-3 complexes Mus musculus ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
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?

Synonyms

Synonyms Comment Organism
phosphatidylinositol-4-kinase type II alpha
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Mus musculus
PI4KIIalpha
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Mus musculus