Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.67 extracted from

  • Lundberg, G.A.; Jergil, B.; Sundler, R.
    Subcellular localization and enzymatic properties of rat liver phosphatidylinositol-4-phosphate kinase (1985), Biochim. Biophys. Acta, 846, 379-387.
    View publication on PubMed
Search for more literature for 2.7.1.67

Inhibitors

Inhibitors Comment Organism Structure
Triton X-100
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information no or minimal activity can be ascribed to mitochondria, lysosomes, Golgi membranes or endoplasmic reticulum Rattus norvegicus
-
-
plasma membrane
-
 Rattus norvegicus 5886
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ preferred divalent cation, maximal activity at 15 mM Rattus norvegicus
Mn2+ can only partially replace Mg2+. Activity at 2 mM or 5 mM is approximately 40% of the activity at 15 mM mM MgCl2 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol
-
 Rattus norvegicus ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5 8 activity in presence of 0.25% Triton X-100 Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
5.3 9 pH 5.3: about 80% of maximal activity, pH 8.6: about 60% of maximal activity Rattus norvegicus