Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | competitive inhibitor of Mg2+ | Mus musculus | |
phosphatidylinositol 4,5-bisphosphate | - |
Mus musculus | |
phosphatidylinositol 4-phosphate | - |
Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.14 | - |
ATP | pH 7.1, 25°C | Mus musculus | |
0.62 | - |
GTP | pH 7.1, 25°C | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | integral membrane protein | Mus musculus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | dependent on Mg2+ or Mn2+. Km for Mg2+ is about 5 mM | Mus musculus | |
Mn2+ | dependent on Mg2+ or Mn2+ | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
gel filtration | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
T-lymphocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol | - |
Mus musculus | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? | |
GTP + 1-phosphatidyl-1D-myo-inositol | - |
Mus musculus | GDP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
enzyme is stable | Mus musculus |
33 | - |
3 min, 50% inactivation | Mus musculus |
56 | - |
cell lysate, 5 min, virtually all activity is lost | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | 8 | - |
Mus musculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
12 | - |
Ca2+ | pH 7.1, 25°C | Mus musculus |