Protein Variants | Comment | Organism |
---|---|---|
A109S | the mutant shows about 85% of wild type activity | Streptococcus mutans |
D106A | the activity of the mutant is less than 5% of the activity of wild type enzyme | Streptococcus mutans |
D7A | the mutant shows about 70% of wild type activity | Streptococcus mutans |
D90A | the activity of the mutant is less than 10% of the activity of wild type enzyme | Streptococcus mutans |
D94A | the mutant shows about 65% of wild type activity | Streptococcus mutans |
E38A | the mutant shows about 35% of wild type activity | Streptococcus mutans |
E79A | the mutant shows about 1% of wild type activity | Streptococcus mutans |
E86A | the mutant shows about 1% of wild type activity | Streptococcus mutans |
H44A | the mutant shows about 58% of wild type activity | Streptococcus mutans |
H44E | the mutant shows about 1% of wild type activity | Streptococcus mutans |
H96A | the mutant shows wild type activity | Streptococcus mutans |
K102A | the mutant shows about 80% of wild type activity | Streptococcus mutans |
K105A | the mutant shows about 20% of wild type activity | Streptococcus mutans |
N40A | the mutant shows about 75% of wild type activity | Streptococcus mutans |
N82A | the mutant shows about 1% of wild type activity | Streptococcus mutans |
N87A | the mutant shows about 85% of wild type activity | Streptococcus mutans |
R39A | the mutant shows about 85% of wild type activity | Streptococcus mutans |
S11A | the mutant shows about 95% of wild type activity | Streptococcus mutans |
S22A | the mutant shows about 105% of wild type activity | Streptococcus mutans |
S23A | the mutant shows wild type activity | Streptococcus mutans |
S83A | the mutant shows about 105% of wild type activity | Streptococcus mutans |
T19A | the mutant shows about 95% of wild type activity | Streptococcus mutans |
T21A | the mutant shows about 95% of wild type activity | Streptococcus mutans |
T29A | the mutant shows about 110% of wild type activity | Streptococcus mutans |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.118 | - |
undecaprenol | at pH 8.0 and 37°C | Streptococcus mutans | |
0.218 | - |
ATP | at pH 8.0 and 37°C | Streptococcus mutans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + undecaprenol | Streptococcus mutans | - |
ADP + undecaprenyl phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus mutans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + undecaprenol | - |
Streptococcus mutans | ADP + undecaprenyl phosphate | - |
? | |
additional information | the enzyme is also a Mg-ADP-dependent undecaprenyl phosphate phosphatase catalyzing the hydrolysis of C55P to C55OH and a free inorganic phosphate | Streptococcus mutans | ? | - |
- |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.4 | - |
ATP | at pH 8.0 and 37°C | Streptococcus mutans | |
4 | - |
undecaprenol | at pH 8.0 and 37°C | Streptococcus mutans |