BRENDA - Enzyme Database show
show all sequences of 2.7.1.59

N-acetyl-D-glucosamine kinase interacts with dynein light-chain roadblock type 1 at Golgi outposts in neuronal dendritic branch points

Islam, M.A.; Sharif, S.R.; Lee, H.; Seog, D.H.; Moon, I.S.; Exp. Mol. Med. 47, e177 (2015)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
expressed in HEK-293T cells
Rattus norvegicus
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ATP + N-acetyl-D-glucosamine
Rattus norvegicus
-
ADP + N-acetyl-D-glucosamine 6-phosphate
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
hippocampus
-
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + N-acetyl-D-glucosamine
-
738177
Rattus norvegicus
ADP + N-acetyl-D-glucosamine 6-phosphate
-
-
-
?
Cloned(Commentary) (protein specific)
Commentary
Organism
expressed in HEK-293T cells
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ATP + N-acetyl-D-glucosamine
Rattus norvegicus
-
ADP + N-acetyl-D-glucosamine 6-phosphate
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
hippocampus
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + N-acetyl-D-glucosamine
-
738177
Rattus norvegicus
ADP + N-acetyl-D-glucosamine 6-phosphate
-
-
-
?
General Information
General Information
Commentary
Organism
physiological function
the enzyme interacts with DYNLRB1 in primary hippocampal neurons
Rattus norvegicus
General Information (protein specific)
General Information
Commentary
Organism
physiological function
the enzyme interacts with DYNLRB1 in primary hippocampal neurons
Rattus norvegicus
Other publictions for EC 2.7.1.59
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
738315
Cao
Role of the N-acetylglucosamin ...
Candida albicans
Fungal Genet. Biol.
92
26-32
2016
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1
1
-
-
-
739441
Felice
Molecular characterization of ...
Candida africana, Candida africana CBS11016, Candida africana UPV/EHU 97135
PLoS ONE
11
e0147902
2016
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3
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738177
Islam
N-acetyl-D-glucosamine kinase ...
Rattus norvegicus
Exp. Mol. Med.
47
e177
2015
-
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1
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1
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1
1
-
-
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738241
Furo
Identification of an N-acetylg ...
Arabidopsis thaliana
FEBS Lett.
589
3258-3262
2015
-
-
1
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4
-
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1
1
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4
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1
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5
1
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4
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1
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4
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1
1
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1
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5
1
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-
-
4
-
-
-
-
-
-
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-
4
4
739072
Sharif
N-acetyl-D-glucosamine kinase ...
Rattus norvegicus
Mol. Cells
38
402-408
2015
-
-
-
-
-
-
-
-
4
-
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1
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2
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1
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1
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4
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1
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1
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1
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-
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-
-
-
-
739073
Islam
N-acetyl-D-glucosamine kinase ...
Homo sapiens
Mol. Cells
38
876-885
2015
-
-
-
-
-
-
-
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1
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2
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1
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1
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1
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1
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1
-
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-
-
-
-
-
-
-
1
1
1
1
-
-
739411
Flores
The gene YALI0E20207g from Yar ...
Yarrowia lipolytica, Yarrowia lipolytica CJM936
PLoS ONE
10
e0122135
2015
-
-
1
-
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4
-
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2
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4
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1
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8
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1
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1
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8
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739070
Lee
The non-canonical effect of N- ...
Rattus norvegicus
Mol. Cells
37
248-256
2014
-
-
-
-
-
-
-
-
1
-
1
1
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2
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5
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1
1
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1
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1
1
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5
-
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1
1
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2
2
-
-
-
739071
Lee
Upregulation of dendritic arbo ...
Rattus norvegicus
Mol. Cells
37
322-329
2014
-
-
1
-
3
-
-
6
-
-
1
1
-
2
-
-
1
-
-
1
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1
1
-
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1
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3
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6
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1
1
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1
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1
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1
1
-
-
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-
-
-
-
-
-
1
1
-
-
-
723600
Rao
N-acetylglucosamine kinase, HX ...
Candida albicans
PLoS ONE
8
e53638
2013
-
-
1
-
1
-
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3
1
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2
-
4
-
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1
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1
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2
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1
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1
1
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1
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3
1
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2
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1
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1
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2
-
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-
1
3
3
1
-
-
722301
Scarcelli
Uptake of radiolabeled GlcNAc ...
Candida albicans, no activity in Saccharomyces cerevisiae
FEMS Yeast Res.
12
305-316
2012
-
-
1
-
1
-
-
-
-
1
-
1
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3
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1
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1
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1
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1
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1
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-
-
722533
Reith
Characterization of an N-acety ...
Clostridium acetobutylicum
J. Bacteriol.
193
5386-5392
2011
-
1
1
-
-
-
1
1
1
1
1
2
-
3
-
-
1
-
-
-
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2
1
1
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1
1
1
1
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1
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1
1
1
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1
-
1
1
1
1
2
-
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-
1
-
-
-
-
2
1
1
-
1
1
1
1
-
-
-
1
1
-
1
1
702223
Blume
Characterization of ligand bin ...
Homo sapiens
Biochemistry
47
13138-13146
2008
-
-
1
-
-
-
-
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1
-
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2
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1
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4
-
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1
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1
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1
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-
4
-
-
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-
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-
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-
-
-
-
675413
Weihofen
Structures of human N-acetylgl ...
Homo sapiens
J. Mol. Biol.
364
388-399
2006
-
-
1
1
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
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1
1
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1
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1
1
1
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-
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-
1
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-
-
-
1
1
-
-
-
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-
-
-
-
-
-
-
-
-
-
659055
Uehara
The N-acetyl-D-glucosamine kin ...
Escherichia coli
J. Bacteriol.
186
7273-7279
2004
-
-
1
-
1
-
1
3
1
1
-
1
-
2
-
-
1
-
-
-
2
1
4
-
1
-
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1
-
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1
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1
1
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1
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1
-
3
1
1
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1
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1
-
-
2
1
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
641703
Berger
Structure and function of N-ac ...
Mus musculus
Eur. J. Biochem.
269
4212-4218
2002
-
-
1
-
6
-
-
1
-
-
2
1
-
2
-
-
1
-
-
-
-
-
2
-
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1
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6
-
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1
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2
1
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1
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-
2
-
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-
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-
641702
Yamada-Okabe
Identification and characteriz ...
Candida albicans, Homo sapiens
Eur. J. Biochem.
268
2498-2505
2001
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-
2
-
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4
-
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2
-
9
-
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2
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7
-
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2
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2
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4
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2
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2
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7
-
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-
2
-
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-
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-
-
-
-
641701
Hinderlich
Molecular cloning and characte ...
Homo sapiens, Mus musculus
Eur. J. Biochem.
267
3301-3308
2000
-
-
2
-
-
-
2
-
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3
2
-
6
-
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1
-
-
17
2
-
4
-
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-
-
2
-
-
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-
2
-
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-
3
2
-
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-
1
-
17
2
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641700
Hinderlich
Purification and characterizat ...
Rattus norvegicus
Eur. J. Biochem.
252
133-139
1998
-
-
-
-
-
-
6
2
1
-
2
1
-
2
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1
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-
1
1
-
2
1
-
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-
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6
-
2
1
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2
1
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1
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1
1
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2
1
-
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-
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-
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-
-
-
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-
-
246598
Weidanz
N-Acetylglucosamine kinase and ...
Homo sapiens, Plasmodium falciparum
Br. J. Haematol.
95
645-653
1996
-
-
-
-
-
-
2
1
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2
-
2
-
5
-
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3
2
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2
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2
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1
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2
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2
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3
2
-
2
-
-
-
-
-
-
-
-
-
-
-
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641696
Rai
Purification and some properti ...
Candida albicans
Biochim. Biophys. Acta
614
350-356
1980
-
-
-
-
-
2
2
2
-
5
1
1
-
3
-
-
1
-
-
-
1
1
4
-
-
-
1
-
1
-
-
-
-
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-
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-
-
2
-
2
-
2
-
5
1
1
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1
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-
1
1
4
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
641697
Allen
Kinetic characterization of N- ...
Rattus norvegicus
Biochem. J.
185
577-582
1980
-
-
-
-
-
-
3
8
1
1
-
1
-
2
-
-
1
-
-
4
-
-
3
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
3
-
8
1
1
-
1
-
-
-
1
-
4
-
-
3
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
641698
Allen
The isolation and preliminary ...
Rattus norvegicus
Biochem. J.
185
565-575
1980
-
-
-
-
-
-
-
-
-
-
2
1
-
2
-
-
-
-
-
4
2
1
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
2
1
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-
-
4
2
1
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641695
Datta
-
N-Acetyl-D-glucosamine kinase ...
Sus scrofa
Methods Enzymol.
42c
58-62
1975
2
-
-
-
-
1
7
2
-
4
-
1
-
1
-
-
1
-
-
1
1
1
3
-
-
-
1
-
1
-
-
-
-
-
-
2
-
-
-
-
-
1
-
7
-
2
-
4
-
1
-
-
-
1
-
1
1
1
3
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
641694
Gindzienski
Purification and properties of ...
Homo sapiens
Eur. J. Biochem.
43
155-160
1974
-
-
-
-
-
1
1
2
-
4
1
1
-
2
-
-
1
-
-
2
1
2
3
-
-
-
1
-
1
-
1
-
-
-
-
-
-
-
-
-
-
1
-
1
-
2
-
4
1
1
-
-
-
1
-
2
1
2
3
-
-
-
1
-
1
-
1
-
-
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-
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641693
Datta
Studies on hog spleen N-acetyl ...
Capra hircus, Sus scrofa
Biochim. Biophys. Acta
220
51-60
1970
2
-
-
-
-
2
8
2
-
4
-
2
-
2
-
-
1
-
-
9
3
1
6
-
-
-
1
-
1
-
-
-
1
-
-
2
-
-
-
-
-
2
-
8
1
2
-
4
-
2
-
-
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1
-
9
3
1
6
-
-
-
1
-
1
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-
-
-
-
-
-
-
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641691
Barkulis
-
N-Acetyl-D-glucosamine kinase. ...
Streptococcus pyogenes, Streptococcus pyogenes 523
Methods Enzymol.
9
415-420
1966
1
-
-
-
-
3
3
2
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-
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2
-
2
-
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1
-
-
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1
1
6
-
-
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2
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1
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-
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2
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1
-
-
-
-
-
3
-
3
2
2
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-
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2
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1
-
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1
1
6
-
-
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2
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1
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-
-
-
-
-
-
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641692
Asensio
-
N-Acetyl-D-glucosamine kinase. ...
Escherichia coli
Methods Enzymol.
9
421-425
1966
-
-
-
-
-
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3
4
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1
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1
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1
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1
1
4
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1
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1
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1
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2
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3
2
4
-
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1
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1
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1
1
4
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1
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1
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1
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