Literature summary for 2.7.1.5 extracted from

Wen, L.; Zang, L.; Huang, K.; Li, S.; Wang, R.; Wang, P.
Efficient enzymatic synthesis of L-rhamnulose and L-fuculose (2016), Bioorg. Med. Chem. Lett., 26, 969-972.

Search for more literature for 2.7.1.5

Application

Application	Comment	Organism
synthesis	production of L-Rhamnulose (6-deoxy-L-arabino-2-hexulose) and L-fuculose (6-deoxy-L-lyxo-2-hexulose) from L-rhamnose and L-fucose. First, isomerization of L-rhamnose to L-rhamnulose, or L-fucose to L-fuculose is combined with a targeted phosphorylation reaction catalyzed by L-rhamnulose kinase (RhaB). The by-products (ATP and ADP) are selectively removed by silver nitrate precipitation method. In the second step, the phosphate group is hydrolyzed to produce L-rhamnulose or L-fuculose with purity exceeding 99% in more than 80% yield	Thermotoga maritima MSB8

Organism

Organism	UniProt	Comment	Textmining
Thermotoga maritima MSB8	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + L-fuculose	81.3% of the activity with L-rhamnulose	Thermotoga maritima MSB8	ADP + L-fuculose 1-phosphate	-	?
ATP + L-rhamnulose	-	Thermotoga maritima MSB8	ADP + L-rhamnulose 1-phosphate	-	?
additional information	no substrates: L-rhamnose, L-fucose	Thermotoga maritima MSB8	?	-	?

Synonyms

Synonyms	Comment	Organism
RhaB	-	Thermotoga maritima MSB8

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Release 2023.1 (January 2023)