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Literature summary for 2.7.1.48 extracted from

  • Qimron, U.; Kulczyk, A.W.; Hamdan, S.M.; Tabor, S.; Richardson, C.C.
    Inadequate inhibition of host RNA polymerase restricts T7 bacteriophage growth on hosts overexpressing udk (2008), Mol. Microbiol., 67, 448-457.
    View publication on PubMed

Application

Application Comment Organism
biotechnology overexpression of gene udk encoding uridine/cytidine kinase interferes with T7 bacteriophage growth. This inhibition can be overcome by inhibition of host RNA polymerase by overexpression of gene 2 or by treatment with rifampicin. General model for the requirement of host RNA polymerase inhibition Escherichia coli

Protein Variants

Protein Variants Comment Organism
additional information overexpression of gene udk encoding uridine/cytidine kinase interferes with T7 bacteriophage growth. This inhibition can be overcome by inhibition of host RNA polymerase by overexpression of gene 2 or by treatment with rifampicin Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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-
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Synonyms

Synonyms Comment Organism
Udk
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Escherichia coli