Literature summary for 2.7.1.40 extracted from

Krzysciak, W.; Papie?, M.; Jurczak, A.; Koscielniak, D.; Vyhouskaya, P.; Zagorska-Swiezy, K.; Skalniak, A.
Relationship between pyruvate kinase activity and cariogenic biofilm formation in Streptococcus mutans biotypes in caries patients (2017), Front. Microbiol., 8, 856 .

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ADP + phosphoenolpyruvate	Homo sapiens	-	ATP + pyruvate	-	ir

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P30613	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ADP + phosphoenolpyruvate	-	Homo sapiens	ATP + pyruvate	-	ir

Expression

Organism	Comment	Expression
Homo sapiens	in children, pyruvate kinase (PK) activity increases significantly in dental plaque corresponding with the caries progression. Streptococcus mutans (MS) and its biotype I are the strains most frequently found in dental plaque of young children. The correlation between the level of Streptococcus mutans in dental plaque and PK activity is both statistically significant and positive	up

General Information

General Information	Comment	Organism
physiological function	relationship between pyruvate kinase activity and cariogenic biofilm formation in Streptococcus mutans biotypes in caries patients, analysis of pyruvate kinase activity with respect to caries severity, statistical analysis, overview	Homo sapiens

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Release 2023.1 (January 2023)