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Literature summary for 2.7.1.40 extracted from
- Faecal dimeric M2 pyruvate kinase in colorectal cancer and polyps correlates with tumour staging and surgical intervention (2008), Colorectal Dis., 10, 244-248.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | faecal tumour M2-PK is a highly sensitive marker for colorectal cancer and larger polyps | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphoenolpyruvate | Homo sapiens | - |
ATP + pyruvate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| feces | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphoenolpyruvate | - |
Homo sapiens | ATP + pyruvate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| M2 pyruvate kinase | - |
Homo sapiens |
| tumour M2-PK | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Homo sapiens | |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | patients with colorectal adenocarcinoma have the highest median faecal tumour M2-PK level | up |
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Release 2023.1 (January 2023)
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