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Literature summary for 2.7.1.40 extracted from
- Properties of pyruvate kinase from immature pod wall of chickpea (1989), Plant Physiol. Biochem., 27, 703-711.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| alanine | activation | Cicer arietinum |  |
| glutamine | activation | Cicer arietinum | |
| glycine | activation | Cicer arietinum | |
| methionine | activation | Cicer arietinum | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Cicer arietinum | |
| citrate | - |
Cicer arietinum | |
| fructose 1,6-diphosphate | - |
Cicer arietinum | |
| L-glutamate | - |
Cicer arietinum | |
| oxalate | - |
Cicer arietinum | |
| oxaloacetate | - |
Cicer arietinum | |
| UTP | - |
Cicer arietinum | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.049 | 0.1 | IDP | cosubstrate phosphoenolpyruvate | Cicer arietinum | |
| 0.16 | 0.17 | ADP | - |
Cicer arietinum | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| divalent cation | requirement | Cicer arietinum | |
| divalent cation | requires both a divalent and a monovalent cation | Cicer arietinum | |
| monovalent cation | requirement | Cicer arietinum | |
| monovalent cation | requires both a divalent and a monovalent cation | Cicer arietinum |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 200000 | - |
gel filtration | Cicer arietinum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphoenolpyruvate | Cicer arietinum | probably involved in supplying additional carbon-skeletons for ammonium assimilation | ATP + pyruvate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cicer arietinum | - |
chickpea | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Cicer arietinum |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pod | - |
Cicer arietinum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ADP + phosphoenolpyruvate | best nucleoside diphosphate substrate | Cicer arietinum | ATP + pyruvate | - |
? | |
| ADP + phosphoenolpyruvate | probably involved in supplying additional carbon-skeletons for ammonium assimilation | Cicer arietinum | ATP + pyruvate | - |
? | |
| GDP + phosphoenolpyruvate | less effective than ADP | Cicer arietinum | GTP + pyruvate | - |
? | |
| IDP + phosphoenolpyruvate | - |
Cicer arietinum | ITP + pyruvate | - |
? | |
| UDP + phosphoenolpyruvate | less effective than ADP | Cicer arietinum | UTP + pyruvate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.8 | - |
- |
Cicer arietinum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| AMP | activation | Cicer arietinum | |
| CMP | activation | Cicer arietinum | |
| GDP | activation | Cicer arietinum | |
| GMP | activation | Cicer arietinum | |
| UDP | activation | Cicer arietinum | |
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Release 2023.1 (January 2023)
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