Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NH4+ | 30% of the activity obtained with 0.5 M K+ | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-amino-beta-hydroxy valeric acid | - |
Escherichia coli | |
L-2-aminobutyric acid | 40 mM, 50% inhibition | Escherichia coli | |
L-Thr | - |
Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.3 | - |
ATP | pH 7.8, 27°C | Escherichia coli | |
0.3 | - |
L-homoserine | pH 7.8, 27°C | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
K+ | activates | Escherichia coli | |
Mg2+ | absolute requirement, optimal activity between 10 mM and 20 mM | Escherichia coli |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
60000 | - |
gel filtration | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
K-12 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + L-homoserine | - |
Escherichia coli | ADP + O-phospho-L-homoserine | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
57 | - |
half-life is 10 min in absence of L-Thr ot L-homoserine | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
- |
Escherichia coli |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
1 | - |
L-Thr | pH 7.8, 27°C | Escherichia coli |