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Literature summary for 2.7.1.36 extracted from

  • Suarez, D.; Garcia-Peregrin, E.; Mayor, F.
    Mevalonate kinase from Pinus pinaster seedlings (1974), Phytochemistry, 13, 1059-1063.
No PubMed abstract available
Search for more literature for 2.7.1.36

Inhibitors

Inhibitors Comment Organism Structure
EDTA 10 mM, almost complete inhibition Pinus pinaster
Mn2+ inhibition at 10 mM in crude extracts Pinus pinaster

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.08
-
 mevalonate pH 7.9, 37°C Pinus pinaster
0.14
-
 ATP pH 7.9, 37°C Pinus pinaster

Organism

Organism UniProt Comment Textmining
Pinus pinaster
-
-
-

Purification (Commentary)

Purification (Comment) Organism
protamine sulfate, ammonium sulfate, Sephadex G-100 Pinus pinaster

Source Tissue

Source Tissue Comment Organism Textmining
seedling
-
 Pinus pinaster
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 0.132 dpm/mg Pinus pinaster

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + mevalonate no activity with GTP Pinus pinaster ADP + phosphomevalonate
-
 ?
ATP + mevalonate no activity with ITP, UTP and ADP Pinus pinaster ADP + phosphomevalonate
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Pinus pinaster

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.8 8
-
 Pinus pinaster