Literature summary for 2.7.1.33 extracted from

Li, B.; Tempel, W.; Smil, D.; Bolshan, Y.; Schapira, M.; Park, H.W.
Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides (2013), Proteins, 81, 1466-1472.

Search for more literature for 2.7.1.33

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3) cells	Klebsiella pneumoniae

Crystallization (Commentary)

Crystallization (Comment)	Organism
in complex with N-pyridin-3-ylmethylpantothenamide, sitting drop vapor diffusion method, using 20% (w/v) PEG3350 and 0.2 M tri-lithium citrate	Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + (R)-pantothenate	Klebsiella pneumoniae	-	ADP + (R)-4'-phosphopantothenate	-	?
ATP + (R)-pantothenate	Klebsiella pneumoniae 342	-	ADP + (R)-4'-phosphopantothenate	-	?

Organism

Organism	UniProt	Comment	Textmining
Klebsiella pneumoniae	B5XYG3	-	-
Klebsiella pneumoniae 342	B5XYG3	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-NTA resin column chromatography and Superdex 75 gel filtration	Klebsiella pneumoniae

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + (R)-pantothenate	-	Klebsiella pneumoniae	ADP + (R)-4'-phosphopantothenate	-	?
ATP + (R)-pantothenate	-	Klebsiella pneumoniae 342	ADP + (R)-4'-phosphopantothenate	-	?

Synonyms

Synonyms	Comment	Organism
PanK	-	Klebsiella pneumoniae

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Release 2023.1 (January 2023)