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Literature summary for 2.7.1.33 extracted from

  • Awuah, E.; Ma, E.; Hoegl, A.; Vong, K.; Habib, E.; Auclair, K.
    Exploring structural motifs necessary for substrate binding in the active site of Escherichia coli pantothenate kinase (2014), Bioorg. Med. Chem., 22, 3083-3090.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.33

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.021
-
 (R)-pantothenate at pH 7.6, temperature not specified in the publication Escherichia coli
0.022
-
 (2R)-2,4-dihydroxy-N-(3-[[3-(1H-imidazol-1-yl)propyl]amino]-3-oxopropyl)-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.032
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(3-phenylpropyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.033
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.036
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.039
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-[(3-methylpyridin-2-yl)amino]-3-oxopropyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.043
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(phenylamino)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.05
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-2-ylmethyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.06
-
 pantheteine at pH 7.6, temperature not specified in the publication Escherichia coli
0.067
-
 (2R)-N-[3-(benzylamino)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.11
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(pyridin-2-yl)ethyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.11
-
 (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hept-6-ynamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.12
-
 N-[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alanyl-N-pentylglycinamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.13
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-4-ylmethyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.19
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[(1-pentyl-1H-1,2,3-triazol-4-yl)methyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.2
-
 (2R)-N-[3-(1,3-dihydro-2H-isoindol-2-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.23
-
 (2S)-2-hydroxy-3-(hydroxymethyl)-3-methyl-N-[3-oxo-3-(pentylamino)propyl]pentanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.24
-
 (2R)-N-[3-[(2-butanamidoethyl)amino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.35
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[3-(morpholin-4-yl)propyl]amino]-3-oxopropyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.4
-
 (2R)-N-[3-(2,3-dihydro-1H-indol-1-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.45
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pyrimidin-4-ylamino)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.59
-
 (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hex-5-enamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.7
-
 3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]-2-(pentylamino)propanoate at pH 7.6, temperature not specified in the publication Escherichia coli
1
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-(1-propyl-1H-1,2,3-triazol-4-yl)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[(piperidin-4-yl)methyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(piperazin-1-yl)ethyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.2
-
 (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hex-5-enamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.2
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[2-oxo-2-(pentylamino)ethyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + (R)-pantothenate Escherichia coli
-
 ADP + (R)-4'-phosphopantothenate
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli P0A6I3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[(piperidin-4-yl)methyl]amino]propyl)butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-[[(piperidin-4-yl)methyl]amino]propyl)amino]butyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(piperazin-1-yl)ethyl]amino]propyl)butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-[[2-(piperazin-1-yl)ethyl]amino]propyl)amino]butyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(pyridin-2-yl)ethyl]amino]propyl)butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-[[2-(pyridin-2-yl)ethyl]amino]propyl)amino]butyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[2-oxo-2-(pentylamino)ethyl]amino]propyl)butanamide
-
 Escherichia coli ADP + N2-(3-[[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]amino]propyl)-N-pentylglycinamide
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[3-(morpholin-4-yl)propyl]amino]-3-oxopropyl)butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-[(3-[[3-(morpholin-4-yl)propyl]amino]-3-oxopropyl)amino]-4-oxobutyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[(1-pentyl-1H-1,2,3-triazol-4-yl)methyl]butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[(1-pentyl-1H-1,2,3-triazol-4-yl)methyl]amino]butyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-(1-propyl-1H-1,2,3-triazol-4-yl)propyl]butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-(1-propyl-1H-1,2,3-triazol-4-yl)propyl]amino]butyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide
-
 Escherichia coli ADP + N3-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-pentyl-beta-alaninamide
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(phenylamino)propyl]butanamide
-
 Escherichia coli ADP + N3-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-phenyl-beta-alaninamide
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pyrimidin-4-ylamino)propyl]butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-([3-oxo-3-[(pyrimidin-4-yl)amino]propyl]amino)butyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(3-phenylpropyl)amino]propyl]butanamide
-
 Escherichia coli ADP + N3-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(3-phenylpropyl)-beta-alaninamide
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-2-ylmethyl)amino]propyl]butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-[[(pyridin-2-yl)methyl]amino]propyl)amino]butyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl]butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-[[(pyridin-3-yl)methyl]amino]propyl)amino]butyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-4-ylmethyl)amino]propyl]butanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-2,2-dimethyl-4-oxo-4-[(3-oxo-3-[[(pyridin-4-yl)methyl]amino]propyl)amino]butyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-[(3-methylpyridin-2-yl)amino]-3-oxopropyl]butanamide
-
 Escherichia coli ADP + (3R)-4-([3-[(3-aminopyridin-2-yl)amino]-3-oxopropyl]amino)-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen phosphate
-
 ?
ATP + (2R)-2,4-dihydroxy-N-(3-[[3-(1H-imidazol-1-yl)propyl]amino]-3-oxopropyl)-3,3-dimethylbutanamide
-
 Escherichia coli ADP + (3R)-3-hydroxy-4-[(3-[[3-(1H-imidazol-1-yl)propyl]amino]-3-oxopropyl)amino]-2,2-dimethyl-4-oxobutyl dihydrogen phosphate
-
 ?
ATP + (2R)-N-[3-(1,3-dihydro-2H-isoindol-2-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
-
 Escherichia coli ADP + (3R)-4-[[3-(1,3-dihydro-2H-isoindol-2-yl)-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen phosphate
-
 ?
ATP + (2R)-N-[3-(2,3-dihydro-1H-indol-1-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
-
 Escherichia coli ADP + (3R)-4-[[3-(2,3-dihydro-1H-indol-1-yl)-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen phosphate
-
 ?
ATP + (2R)-N-[3-(benzylamino)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
-
 Escherichia coli ADP + N-benzyl-N3-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide
-
 ?
ATP + (2R)-N-[3-[(2-butanamidoethyl)amino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide
-
 Escherichia coli ADP + N-(2-butanamidoethyl)-N3-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide
-
 ?
ATP + (2S)-2-hydroxy-3-(hydroxymethyl)-3-methyl-N-[3-oxo-3-(pentylamino)propyl]pentanamide
-
 Escherichia coli ADP + N3-[(2S,3S)-2-hydroxy-3-methyl-3-[(phosphonooxy)methyl]pentanoyl]-N-pentyl-beta-alaninamide
-
 ?
ATP + (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hept-6-ynamide
-
 Escherichia coli ADP + N3-[(2S,3S)-3-ethyl-2-hydroxy-3-[(phosphonooxy)methyl]hept-6-ynoyl]-N-pentyl-beta-alaninamide
-
 ?
ATP + (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hex-5-enamide
-
 Escherichia coli ADP + N3-[(2S)-3-ethyl-2-hydroxy-3-[(phosphonooxy)methyl]hex-5-enoyl]-N-pentyl-beta-alaninamide
-
 ?
ATP + (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]pentanamide
-
 Escherichia coli ADP + N3-[(2S)-3-ethyl-2-hydroxy-3-[(phosphonooxy)methyl]pentanoyl]-N-pentyl-beta-alaninamide
-
 ?
ATP + (R)-pantothenate
-
 Escherichia coli ADP + (R)-4'-phosphopantothenate
-
 ?
ATP + 3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]-2-(pentylamino)propanoate
-
 Escherichia coli ADP + 3-[[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]amino]-2-(pentylamino)propanoate
-
 ?
ATP + N-[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alanyl-N-pentylglycinamide
-
 Escherichia coli ADP + N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl-N-pentylglycinamide
-
 ?
ATP + pantheteine
-
 Escherichia coli ?
-
 ?

Synonyms

Synonyms Comment Organism
PanK
-
 Escherichia coli

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.13
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[2-oxo-2-(pentylamino)ethyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.18
-
 (2R)-N-[3-(2,3-dihydro-1H-indol-1-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.23
-
 3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]-2-(pentylamino)propanoate at pH 7.6, temperature not specified in the publication Escherichia coli
0.28
-
 (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hex-5-enamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.45
-
 (2R)-N-[3-(1,3-dihydro-2H-isoindol-2-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.46
-
 (2R)-2,4-dihydroxy-N-(3-[[3-(1H-imidazol-1-yl)propyl]amino]-3-oxopropyl)-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.49
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-(1-propyl-1H-1,2,3-triazol-4-yl)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.75
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(piperazin-1-yl)ethyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.78
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-[(3-methylpyridin-2-yl)amino]-3-oxopropyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.89
-
 (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hex-5-enamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.93
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.94
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-4-ylmethyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.96
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[(1-pentyl-1H-1,2,3-triazol-4-yl)methyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.02
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(phenylamino)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.02
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-2-ylmethyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.03
-
 pantheteine at pH 7.6, temperature not specified in the publication Escherichia coli
1.03
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[3-(morpholin-4-yl)propyl]amino]-3-oxopropyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.04
-
 (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hept-6-ynamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.07
-
 (R)-pantothenate at pH 7.6, temperature not specified in the publication Escherichia coli
1.09
-
 (2R)-N-[3-[(2-butanamidoethyl)amino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.12
-
 N-[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alanyl-N-pentylglycinamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.13
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(3-phenylpropyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.15
-
 (2R)-N-[3-(benzylamino)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.15
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(pyridin-2-yl)ethyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.17
-
 (2S)-2-hydroxy-3-(hydroxymethyl)-3-methyl-N-[3-oxo-3-(pentylamino)propyl]pentanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.19
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[(piperidin-4-yl)methyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.24
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.44
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pyrimidin-4-ylamino)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
0.1
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[2-oxo-2-(pentylamino)ethyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.2
-
 (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hex-5-enamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.3
-
 3-[[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]-2-(pentylamino)propanoate at pH 7.6, temperature not specified in the publication Escherichia coli
0.3
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(piperazin-1-yl)ethyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.4
-
 (2R)-N-[3-(2,3-dihydro-1H-indol-1-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.5
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-(1-propyl-1H-1,2,3-triazol-4-yl)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
0.5
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[(piperidin-4-yl)methyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.5
-
 (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hex-5-enamide at pH 7.6, temperature not specified in the publication Escherichia coli
1.9
-
 (2R)-N-[3-(1,3-dihydro-2H-isoindol-2-yl)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
2.9
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-[[3-(morpholin-4-yl)propyl]amino]-3-oxopropyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
3.2
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pyrimidin-4-ylamino)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
4.5
-
 (2R)-N-[3-[(2-butanamidoethyl)amino]-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
5.1
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[(1-pentyl-1H-1,2,3-triazol-4-yl)methyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
5.1
-
 (2S)-2-hydroxy-3-(hydroxymethyl)-3-methyl-N-[3-oxo-3-(pentylamino)propyl]pentanamide at pH 7.6, temperature not specified in the publication Escherichia coli
7
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-4-ylmethyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
9
-
 (2S)-3-ethyl-2-hydroxy-3-(hydroxymethyl)-N-[3-oxo-3-(pentylamino)propyl]hept-6-ynamide at pH 7.6, temperature not specified in the publication Escherichia coli
10
-
 N-[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alanyl-N-pentylglycinamide at pH 7.6, temperature not specified in the publication Escherichia coli
11
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-(3-oxo-3-[[2-(pyridin-2-yl)ethyl]amino]propyl)butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
17
-
 pantheteine at pH 7.6, temperature not specified in the publication Escherichia coli
17
-
 (2R)-N-[3-(benzylamino)-3-oxopropyl]-2,4-dihydroxy-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
20
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-[(3-methylpyridin-2-yl)amino]-3-oxopropyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
20
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-2-ylmethyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
21
-
 (2R)-2,4-dihydroxy-N-(3-[[3-(1H-imidazol-1-yl)propyl]amino]-3-oxopropyl)-3,3-dimethylbutanamide at pH 7.6, temperature not specified in the publication Escherichia coli
24
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(phenylamino)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
26
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(pentylamino)propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
35
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(3-phenylpropyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
38
-
 (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl]butanamide at pH 7.6, temperature not specified in the publication Escherichia coli
50
-
 (R)-pantothenate at pH 7.6, temperature not specified in the publication Escherichia coli