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Literature summary for 2.7.1.32 extracted from

  • Choi, M.G.; Kurnov, V.; Kersting, M.C.; Sreenivas, A.; Carman, G.M.
    Phosphorylation of the yeast choline kinase by protein kinase C. Identification of Ser25 and Ser30 as major sites of phosphorylation (2005), J. Biol. Chem., 280, 26105-26112.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.32

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Sf9 cells Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
S25A mutation results in 32% decrease of phosphatidylcholine synthesis compared to the wild type enzyme Saccharomyces cerevisiae
S25D mutation results in 14% increase of phosphatidylcholine synthesis compared to the wild type enzyme Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae KS106
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Con A column chromatography, Affi-Gel Blue gel filtration and Mono Q column chromatography Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + choline
-
 Saccharomyces cerevisiae ADP + O-phosphocholine
-
 ?
ATP + choline
-
 Saccharomyces cerevisiae KS106 ADP + O-phosphocholine
-
 ?

Synonyms

Synonyms Comment Organism
ChoK
-
 Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Saccharomyces cerevisiae