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Literature summary for 2.7.1.30 extracted from

  • Ohira, R.H.; Dipple, K.M.; Zhang, Y.H.; McCabe, E.R.
    Human and murine glycerol kinase: influence of exon 18 alternative splicing on function (2005), Biochem. Biophys. Res. Commun., 331, 239-246.
    View publication on PubMed
Search for more literature for 2.7.1.30

Cloned(Commentary)

Cloned (Comment) Organism
both isoforms expressed in COS-7 cells Mus musculus
both isoforms expressed in COS-7 cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion isoform GK+EX18 Mus musculus 5739
-
mitochondrion isoform GK+EX18 Homo sapiens 5739
-
additional information GK-EX18 has a diffuse expression pattern Mus musculus
-
-
additional information GK-EX18 has a diffuse expression pattern Homo sapiens
-
-
perinuclear space isoform GK+EX18 Mus musculus
-
-
perinuclear space isoform GK+EX18 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + glycerol Mus musculus involved in fat and carbohydrate metabolism, glycerol 3-phosphate is important for the synthesis of glycerides, glycerol lipids and dihydroxyacetone phosphate ADP + sn-glycerol 3-phosphate
-
 ?
ATP + glycerol Homo sapiens involved in fat and carbohydrate metabolism, glycerol 3-phosphate is important for the synthesis of glycerides, glycerol lipids and dihydroxyacetone phosphate ADP + sn-glycerol 3-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell lung cell line Homo sapiens
-
adult stem cell SS6-2 cell, stem cells from fat with myotube characteristics Homo sapiens
-
brown fat newborn, expresses only isoform GK-EX18 Mus musculus
-
Fanconi anemia lymphoid cell line from patients with enzyme deficiency and normal individuals Homo sapiens
-
G-401 cell kidney cell line Homo sapiens
-
G-402 cell kidney cell line, expresses only isoform GK+EX18 Homo sapiens
-
heart increased level during embryonic development Mus musculus
-
Hep-G2 cell adult hepatoblastoma cell line Homo sapiens
-
liver adult and newborn, expresses only isoform GK-EX18 Mus musculus
-
testis expresses only isoform GK+EX18 Homo sapiens
-
WRL-68 cell fetal liver cell line Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + glycerol
-
 Mus musculus ADP + sn-glycerol 3-phosphate
-
 ?
ATP + glycerol
-
 Homo sapiens ADP + sn-glycerol 3-phosphate
-
 ?
ATP + glycerol involved in fat and carbohydrate metabolism, glycerol 3-phosphate is important for the synthesis of glycerides, glycerol lipids and dihydroxyacetone phosphate Mus musculus ADP + sn-glycerol 3-phosphate
-
 ?
ATP + glycerol involved in fat and carbohydrate metabolism, glycerol 3-phosphate is important for the synthesis of glycerides, glycerol lipids and dihydroxyacetone phosphate Homo sapiens ADP + sn-glycerol 3-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
More two alternatively spliced forms, one with a 87 bp insertion corresponding to exon 18 (GK+EX18), and one without insertion (GK-EX18) Mus musculus
More two alternatively spliced forms, one with a 87 bp insertion corresponding to exon 18 (GK+EX18), and one without insertion (GK-EX18) Homo sapiens