Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.1.3 extracted from

  • Bais, R.; James, H.M.; Rofe, A.M.; Conyers, A.J.
    The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol (1985), Biochem. J., 230, 53-60.
    View publication on PubMed
Search for more literature for 2.7.1.3

Inhibitors

Inhibitors Comment Organism Structure
N-ethylmaleimide
-
 Homo sapiens
PCMB
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.86
-
 D-fructose 37°C, pH 7.5 Homo sapiens
6
-
 D-xylulose 37°C, pH 7.5 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
39000
-
 2 * 39000, SDS-PAGE Homo sapiens
75000
-
 gel filtration Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + D-fructose Homo sapiens role in formation of glycoaldehyde ADP + D-fructose 1-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
heart
-
 Homo sapiens
-
kidney
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
muscle
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
9.4
-
-
 Homo sapiens

Storage Stability

Storage Stability Organism
-20°C Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-fructose
-
 Homo sapiens ADP + D-fructose 1-phosphate
-
 ?
ATP + D-fructose role in formation of glycoaldehyde Homo sapiens ADP + D-fructose 1-phosphate
-
 ?
ATP + D-xylulose
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 39000, SDS-PAGE Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens