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Literature summary for 2.7.1.25 extracted from

  • Li, H.; Li, Z.; Ma, J.; Sun, M.
    Adenosine-5'-phosphosulfate kinase from Thermobifida fusca (2014), Appl. Biochem. Microbiol., 50, 563-570.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
adenosine-5'-phosphosulfate substrate inhibition Thermobifida fusca
additional information not inhibited by ATP Thermobifida fusca

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.46
-
ATP at pH 8.0 and 25°C Thermobifida fusca

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + adenosine-5'-phosphosulfate Thermobifida fusca
-
ADP + 3'-phosphoadenosine 5'-phosphosulfate
-
?

Organism

Organism UniProt Comment Textmining
Thermobifida fusca
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + adenosine-5'-phosphosulfate
-
Thermobifida fusca ADP + 3'-phosphoadenosine 5'-phosphosulfate
-
?

Synonyms

Synonyms Comment Organism
adenosine-5'-phosphosulfate kinase
-
Thermobifida fusca
APS kinase
-
Thermobifida fusca
APSK
-
Thermobifida fusca

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
30 43 10 min incubation at 30°C and 35.5°C do not affect the enzyme's activity, however, treatments of 38.8°C and 41.6°C decrease its activity to 80% and 60% of control, respectively. Temperatures higher than 43°C almost completely deactivate the enzyme. After incubation at 25°C for 17, 26, 41 and 68 h, the enzyme activity is 91%, 109%, 101% and 114% of the control, respectively Thermobifida fusca

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 8
-
Thermobifida fusca