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Literature summary for 2.7.1.24 extracted from

  • Walia, G.; Surolia, A.
    Insights into the regulatory characteristics of the mycobacterial dephosphocoenzyme A kinase: implications for the universal CoA biosynthesis pathway (2011), PLoS ONE, 6, e21390.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
CTP enzymatic activity is regulated by CTP which strongly binds the enzyme at a site overlapping that of the leading substrate, dephosphocoenzyme A, thereby obscuring the binding site and limiting catalysis. 16% residual activity at 1 mM CTP Mycobacterium tuberculosis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
47000
-
3 * 47000, SDS-PAGE Mycobacterium tuberculosis
141000
-
gel filtration Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 3'-dephospho-CoA
-
Mycobacterium tuberculosis ADP + CoA
-
?

Subunits

Subunits Comment Organism
homotrimer 3 * 47000, SDS-PAGE Mycobacterium tuberculosis

Synonyms

Synonyms Comment Organism
CoaE
-
Mycobacterium tuberculosis
dephosphocoenzyme A kinase
-
Mycobacterium tuberculosis