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Literature summary for 2.7.1.24 extracted from

  • Worrall, D.M.; Tubbs, P.K.
    A bifunctional enzyme complex in coenzyme A biosynthesis: purification of pantetheine phosphate adenylyltransferase and dephospho-CoA kinase (1983), Biochem. J., 215, 153-157.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Sus scrofa 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
57000
-
2 * 57000, SDS-PAGE Sus scrofa
115000
-
gel filtration Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.68
-
-
Sus scrofa

Storage Stability

Storage Stability Organism
-20°C, 0.5 mg protein/ml, at least 1 month Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + dephospho-CoA
-
Sus scrofa ADP + CoA
-
?

Subunits

Subunits Comment Organism
dimer 2 * 57000, SDS-PAGE Sus scrofa

Synonyms

Synonyms Comment Organism
More bifunctional enzyme with phosphopantetheine adenylyltransferase activity, EC 2.7.7.3, and dephospho-CoA kinase activity, EC 2.7.1.24 Sus scrofa
More bifunctional enzyme is termed CoA-synthetase Sus scrofa

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Sus scrofa

pI Value

Organism Comment pI Value Maximum pI Value
Sus scrofa
-
-
5.75