BRENDA - Enzyme Database show
show all sequences of 2.7.1.23

Kinetic nature of calmodulin-dependent NAD kinase from pea seedlings

Muto, S.; Z. Pflanzenphysiol. 109, 385-393 (1983)
No PubMed abstract available

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
Calmodulin
Ca2+-calmodulin-dependent enzyme. Half-saturating concentration of calmodulin is 19 ng
Pisum sativum
Inhibitors
Inhibitors
Commentary
Organism
Structure
NADH
-
Pisum sativum
NADPH
-
Pisum sativum
Trifluoperazine
-
Pisum sativum
W-7
-
Pisum sativum
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.11
-
NAD+
pH 8
Pisum sativum
0.18
-
MgATP2-
pH 8
Pisum sativum
0.24
-
ATP
pH 8
Pisum sativum
0.42
-
UTP
pH 8
Pisum sativum
0.59
-
CTP
pH 8
Pisum sativum
1.54
-
ITP
pH 8
Pisum sativum
2.86
-
GTP
pH 8
Pisum sativum
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Ca2+
Ca2+-calmodulin-dependent enzyme. Half-saturating concentration of Ca2+ is 0.07 mM
Pisum sativum
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ATP + NAD+
Pisum sativum
NAD kinase is responsible for the light-induced conversion of NAD to NADP in the chloroplast
ADP + NADP+
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Pisum sativum
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
seedling
-
Pisum sativum
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + NAD+
most effective phosphate donor
641200
Pisum sativum
ADP + NADP+
-
-
-
?
ATP + NAD+
NAD kinase is responsible for the light-induced conversion of NAD to NADP in the chloroplast
641200
Pisum sativum
ADP + NADP+
-
-
-
?
CTP + NAD+
-
641200
Pisum sativum
CDP + NADP+
-
-
-
?
GTP + NAD+
-
641200
Pisum sativum
GDP + NADP+
-
-
-
?
ITP + NAD+
-
641200
Pisum sativum
IDP + NADP+
-
-
-
?
UTP + NAD+
-
641200
Pisum sativum
UDP + NADP+
-
-
-
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
50 mM Hepes-KOH buffer or tricine-KOH buffer
Pisum sativum
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Pisum sativum
Ki Value [mM]
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.01
-
W-7
pH 8
Pisum sativum
0.16
-
NADPH
pH 8
Pisum sativum
1.02
-
NADH
pH 8
Pisum sativum
2.8
-
Trifluoperazine
pH 8
Pisum sativum
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
Calmodulin
Ca2+-calmodulin-dependent enzyme. Half-saturating concentration of calmodulin is 19 ng
Pisum sativum
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Pisum sativum
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
NADH
-
Pisum sativum
NADPH
-
Pisum sativum
Trifluoperazine
-
Pisum sativum
W-7
-
Pisum sativum
Ki Value [mM] (protein specific)
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.01
-
W-7
pH 8
Pisum sativum
0.16
-
NADPH
pH 8
Pisum sativum
1.02
-
NADH
pH 8
Pisum sativum
2.8
-
Trifluoperazine
pH 8
Pisum sativum
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.11
-
NAD+
pH 8
Pisum sativum
0.18
-
MgATP2-
pH 8
Pisum sativum
0.24
-
ATP
pH 8
Pisum sativum
0.42
-
UTP
pH 8
Pisum sativum
0.59
-
CTP
pH 8
Pisum sativum
1.54
-
ITP
pH 8
Pisum sativum
2.86
-
GTP
pH 8
Pisum sativum
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Ca2+
Ca2+-calmodulin-dependent enzyme. Half-saturating concentration of Ca2+ is 0.07 mM
Pisum sativum
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ATP + NAD+
Pisum sativum
NAD kinase is responsible for the light-induced conversion of NAD to NADP in the chloroplast
ADP + NADP+
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
seedling
-
Pisum sativum
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ATP + NAD+
most effective phosphate donor
641200
Pisum sativum
ADP + NADP+
-
-
-
?
ATP + NAD+
NAD kinase is responsible for the light-induced conversion of NAD to NADP in the chloroplast
641200
Pisum sativum
ADP + NADP+
-
-
-
?
CTP + NAD+
-
641200
Pisum sativum
CDP + NADP+
-
-
-
?
GTP + NAD+
-
641200
Pisum sativum
GDP + NADP+
-
-
-
?
ITP + NAD+
-
641200
Pisum sativum
IDP + NADP+
-
-
-
?
UTP + NAD+
-
641200
Pisum sativum
UDP + NADP+
-
-
-
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
50 mM Hepes-KOH buffer or tricine-KOH buffer
Pisum sativum
Other publictions for EC 2.7.1.23
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721766
Jeelani
Biochemical and functional cha ...
Entamoeba histolytica, Entamoeba histolytica HM1: IMSS cl 6
Biochimie
95
309-319
2013
-
-
1
-
-
-
-
4
-
9
2
-
-
7
-
-
1
-
-
-
-
1
14
1
-
-
-
4
1
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
4
-
9
2
-
-
-
-
1
-
-
-
1
14
1
-
-
-
4
1
-
-
1
-
1
1
-
4
4
721255
Gray
NAD kinase regulates the size ...
Mus musculus, Rattus norvegicus
Am. J. Physiol. Endocrinol. Metab.
303
E191-E199
2012
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
5
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
2
-
-
-
-
-
-
-
-
-
-
2
2
-
-
-
722144
Shi
Overexpression of NAD kinases ...
Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13869, Corynebacterium glutamicum subsp. lactofermentum, Corynebacterium glutamicum subsp. lactofermentum JHI3-156
Enzyme Microb. Technol.
51
73-80
2012
-
2
2
-
8
-
6
8
-
-
4
-
-
8
-
-
2
-
-
-
-
-
8
2
-
-
2
8
2
-
2
-
6
-
-
-
2
2
-
-
8
-
-
6
6
8
-
-
4
-
-
-
-
2
-
-
-
-
8
2
-
-
2
8
2
-
2
-
-
2
2
-
8
8
722539
Gao
The cyanobacterial NAD kinase ...
Synechocystis sp.
J. Bacteriol.
194
218-224
2012
-
-
1
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
2
2
-
-
-
723095
Shi
Activating transhydrogenase an ...
Escherichia coli, Escherichia coli MG1655
Metab. Eng.
16C
1-10
2012
-
1
1
-
-
-
-
-
-
-
-
-
-
27
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
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-
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1
1
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-
-
2
-
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-
-
-
-
-
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-
-
-
-
-
-
-
723257
Ohashi
Identification and characteriz ...
Homo sapiens
Nat. Commun.
3
1248
2012
-
-
1
-
-
-
3
3
2
-
3
-
-
4
-
-
1
-
-
13
-
-
13
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
3
-
3
2
-
3
-
-
-
-
1
-
13
-
-
13
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
723781
Gelin
Screening and in situ synthesi ...
Listeria monocytogenes
Structure
20
1107-1117
2012
-
-
1
1
-
-
1
-
-
-
-
-
-
4
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
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-
1
1
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
723167
Ohashi
NADPH regulates human NAD kina ...
Homo sapiens
Mol. Cell. Biochem.
355
57-64
2011
-
-
1
-
-
-
3
1
-
-
2
-
-
4
-
-
1
-
-
-
-
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
3
-
1
-
-
2
-
-
-
-
1
-
-
-
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
706395
Waller
Subcellular and tissue localiz ...
Arabidopsis thaliana
Planta
231
305-317
2010
-
-
-
-
-
-
-
-
2
-
-
-
-
3
-
-
-
-
-
2
-
-
1
-
-
-
-
-
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-
-
1
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-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
721366
Lindner
Polyphosphate/ATP-dependent NA ...
Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032
Appl. Microbiol. Biotechnol.
87
583-593
2010
-
-
1
-
-
-
6
11
-
3
2
-
-
27
-
-
-
-
-
-
-
-
14
1
1
-
1
11
2
-
-
-
2
-
-
-
-
1
-
-
-
-
-
6
2
11
-
3
2
-
-
-
-
-
-
-
-
-
14
1
1
-
1
11
2
-
-
-
-
-
-
-
11
11
706311
Takahashi
Pleiotropic modulation of carb ...
Arabidopsis thaliana
Plant Physiol.
151
100-113
2009
-
-
-
-
-
-
-
-
1
-
-
-
-
3
-
-
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-
1
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1
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1
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1
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1
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1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
691390
Kawai
Structure and function of NAD ...
Arabidopsis thaliana, Archaeoglobus fulgidus, Bacillus subtilis, Candida albicans, Columba livia, Cyberlindnera jadinii, Dictyostelium discoideum, Escherichia coli, Glycine max, Homo sapiens, Lactuca sativa, Listeria monocytogenes, Methanocaldococcus jannaschii, Micrococcus luteus, Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv, Oryza sativa, Pyrococcus horikoshii, Saccharomyces cerevisiae, Salmonella enterica, Schizosaccharomyces pombe, Sorghum sp., Sphingomonas sp. A1, Synechococcus elongatus PCC 6301, Thermotoga maritima, Triticum sp.
Biosci. Biotechnol. Biochem.
72
919-930
2008
4
25
5
1
6
-
6
3
4
8
7
-
-
41
-
-
7
-
-
3
-
-
45
13
-
-
-
3
-
-
-
3
-
-
-
6
30
8
4
1
9
-
-
7
-
3
8
10
9
-
-
-
-
11
-
3
-
-
45
16
-
-
-
3
-
-
-
-
-
1
1
-
-
-
678649
Bonnac
Probing binding requirements o ...
Homo sapiens, Saccharomyces cerevisiae
Bioorg. Med. Chem. Lett.
17
1512-1515
2007
-
-
-
-
-
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1
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4
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1
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-
693013
Pollak
NAD kinase levels control the ...
Homo sapiens
J. Biol. Chem.
282
33562-33571
2007
1
1
1
-
-
-
2
-
1
1
-
-
-
4
-
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-
-
2
-
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2
-
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1
1
1
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2
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1
1
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-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
693014
Poncet-Montange
NAD kinases use substrate-assi ...
Listeria monocytogenes
J. Biol. Chem.
282
33925-33934
2007
-
1
1
1
2
-
3
3
-
1
-
-
-
2
-
-
1
-
-
-
-
-
2
1
-
-
-
6
-
-
-
-
3
-
-
-
1
1
-
1
2
-
-
3
3
3
-
1
-
-
-
-
-
1
-
-
-
-
2
1
-
-
-
6
-
-
-
-
-
-
-
-
-
-
674616
Bieganowski
Synthetic lethal and biochemic ...
Saccharomyces cerevisiae
J. Biol. Chem.
281
22439-22445
2006
-
-
1
-
-
-
-
-
2
-
-
2
-
3
-
-
1
-
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
2
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
677524
Mailloux
In-gel activity staining of ox ...
Pseudomonas fluorescens
Anal. Biochem.
359
210-215
2006
-
1
-
-
-
-
-
-
-
-
-
-
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1
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-
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-
-
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1
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-
-
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-
-
-
-
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-
-
-
-
-
-
-
-
682340
Takahashi
Chloroplast NAD kinase is esse ...
Pisum sativum
Plant Cell Physiol.
47
1678-1682
2006
1
-
-
-
-
-
-
-
1
1
-
-
-
4
-
-
1
-
-
1
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-
1
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-
-
-
-
-
-
-
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-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
682536
Grose
Evidence that feedback inhibit ...
Salmonella enterica
Proc. Natl. Acad. Sci. USA
103
7601-7606
2006
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
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2
-
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-
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-
-
-
-
-
-
-
-
660762
Sakuraba
First archaeal inorganic polyp ...
Pyrococcus horikoshii
Appl. Environ. Microbiol.
71
4352-4358
2005
-
-
1
-
-
-
-
2
-
6
2
-
-
6
-
-
1
-
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-
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8
1
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3
-
1
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-
-
-
-
-
-
660893
Mori
NAD-binding mode and the signi ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Biochem. Biophys. Res. Commun.
327
500-508
2005
-
-
-
1
-
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-
-
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6
-
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-
-
-
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-
-
-
-
661696
Shi
Identification of ATP-NADH kin ...
Saccharomyces cerevisiae
FEBS J.
272
3337-3349
2005
-
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-
-
-
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-
2
-
-
2
-
-
3
-
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1
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1
1
1
-
1
-
1
-
-
-
-
-
-
-
-
-
662376
Mori
Molecular conversion of NAD Ki ...
Escherichia coli, Micrococcus flavus
J. Biol. Chem.
280
24104-24112
2005
-
-
-
-
8
-
-
12
-
-
-
-
-
2
-
-
-
-
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-
8
-
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-
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8
-
3
-
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-
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-
-
-
-
-
-
-
-
-
662661
Liu
Crystal structures of an NAD k ...
Archaeoglobus fulgidus
J. Mol. Biol.
354
289-303
2005
-
-
-
1
-
-
-
-
-
1
-
-
-
2
-
-
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-
-
-
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-
-
-
-
-
-
-
663106
Chai
NADK2, an Arabidopsis chloropl ...
Arabidopsis thaliana
Plant Mol. Biol.
59
553-564
2005
-
-
-
-
1
-
-
-
2
-
-
-
-
3
-
-
-
-
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-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
677335
Oganesyan
Structure of a NAD kinase from ...
Thermotoga maritima
Acta Crystallogr. Sect. F
61
640-646
2005
-
-
1
1
-
-
-
-
-
-
-
1
-
2
-
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-
-
1
-
-
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-
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-
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1
-
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-
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-
-
-
-
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1
-
-
-
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-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
680634
Kawai
MJ0917 in archaeon Methanococc ...
Methanocaldococcus jannaschii
J. Biol. Chem.
280
39200-39207
2005
1
-
1
-
-
-
3
2
-
1
-
-
-
3
-
-
1
-
-
-
1
-
9
-
1
1
-
2
1
1
-
-
-
-
-
1
-
1
-
-
-
-
-
3
-
2
-
1
-
-
-
-
-
1
-
-
1
-
9
-
1
1
-
2
1
1
-
-
-
-
-
-
-
-
660240
Turner
Cloning and characterization o ...
Arabidopsis thaliana
Plant Physiol.
135
1243-1255
2004
2
1
1
-
-
2
2
9
2
1
2
-
-
5
-
-
1
-
-
3
3
1
4
1
-
-
-
-
2
2
-
-
-
-
-
2
1
1
-
-
-
2
-
2
-
9
2
1
2
-
-
-
-
1
-
3
3
1
4
1
-
-
-
-
2
2
-
-
-
-
-
-
-
-
661147
Raffaelli
Characterization of Mycobacter ...
Mycobacterium tuberculosis
Biochemistry
43
7610-7617
2004
-
-
-
-
11
-
3
14
-
-
2
-
-
3
-
-
1
-
-
-
8
1
2
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
11
-
-
3
-
14
-
-
2
-
-
-
-
1
-
-
8
1
2
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
662272
Garavaglia
A novel fold revealed by Mycob ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
J. Biol. Chem.
279
40980-40986
2004
-
-
-
1
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
662482
Mori
Crystallographic studies of My ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
J. Biosci. Bioeng.
98
391-393
2004
-
-
-
1
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
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-
-
-
-
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-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
663065
Karita
Three types of tobacco calmodu ...
Pisum sativum
Plant Cell Physiol.
45
1371-1379
2004
1
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
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-
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-
-
-
-
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-
-
-
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-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
663300
Ochiai
Overexpression, purification, ...
Sphingomonas sp.
Protein Expr. Purif.
36
124-130
2004
-
-
1
-
-
-
4
2
-
5
2
-
-
6
-
-
-
-
-
-
1
-
6
1
-
1
1
2
1
-
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-
-
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1
-
-
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4
-
2
-
5
2
-
-
-
-
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1
-
6
1
-
1
1
2
1
-
-
-
-
-
-
-
-
-
641186
Garavaglia
Allosteric regulation of Bacil ...
Bacillus subtilis
J. Bacteriol.
185
4844-4850
2003
1
-
1
-
-
-
2
1
-
-
2
1
-
2
-
-
-
-
-
-
-
-
9
1
1
1
1
2
1
1
-
1
-
-
-
1
-
1
1
-
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2
-
1
-
-
2
1
-
-
-
-
-
-
-
-
9
1
1
1
1
2
1
1
-
-
-
-
-
-
-
-
641191
Kawai
Primary structure of inorganic ...
Micrococcus flavus
Biosci. Biotechnol. Biochem.
67
1751-1760
2003
-
-
1
-
-
-
-
-
-
-
1
-
-
2
-
-
1
-
-
-
2
-
2
1
-
-
-
-
-
-
-
1
-
-
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-
1
1
-
-
-
-
-
-
-
-
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1
-
-
-
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1
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-
2
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
661914
Mata
Effect of selected phytotoxins ...
Pisum sativum
J. Agric. Food Chem.
51
4559-4562
2003
-
1
-
-
-
-
8
-
-
-
-
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641187
Mori
Crystallization and preliminar ...
Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv
Acta Crystallogr. Sect. D
57
1319-1320
2001
-
-
-
1
-
-
-
-
-
-
-
-
-
162
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
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-
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-
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-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641189
Kawai
Molecular characterization of ...
Escherichia coli, Escherichia coli MG1655
Eur. J. Biochem.
268
4359-4365
2001
-
-
1
-
-
-
5
2
-
-
2
-
-
31
-
-
1
-
-
-
1
-
11
1
1
1
3
2
1
1
-
1
-
-
-
-
-
1
1
-
-
-
-
5
-
2
-
-
2
-
-
-
-
1
-
-
1
-
11
1
1
1
3
2
1
1
-
-
-
-
-
-
-
-
641193
Lerner
Structural and functional char ...
Bos taurus, Homo sapiens
Biochem. Biophys. Res. Commun.
288
69-74
2001
-
-
1
-
-
-
5
2
-
3
3
1
-
5
-
-
2
-
-
5
1
-
4
1
1
-
1
-
1
-
1
2
-
-
-
-
-
1
2
-
-
-
-
5
-
2
-
3
3
1
-
-
-
2
-
5
1
-
4
1
1
-
1
-
1
-
1
-
-
-
-
-
-
-
641203
Gallais
-
Characterization of soluble ca ...
Avena sativa
Aust. J. Plant Physiol.
28
363-371
2001
8
-
-
-
-
1
8
-
-
1
2
1
-
1
-
-
1
-
-
1
1
1
1
-
-
-
-
-
1
2
-
-
-
-
-
8
-
-
-
-
-
1
-
8
-
-
-
1
2
1
-
-
-
1
-
1
1
1
1
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
641192
Stephan
Evidence for the existence of ...
Euglena gracilis, Euglena gracilis Z
Int. J. Biochem. Cell Biol.
32
855-863
2000
1
-
-
-
-
-
4
4
1
-
1
-
-
21
-
-
-
1
-
-
-
-
8
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
4
-
4
1
-
1
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641197
Stephan
-
Changes in NAD+ kinase activit ...
Phaseolus acutifolius, Phaseolus vulgaris
J. Plant Physiol.
157
65-73
2000
2
-
-
-
-
-
-
-
4
2
-
2
-
2
-
-
-
-
-
4
-
-
4
-
-
-
-
-
-
-
-
2
-
-
-
2
-
-
2
-
-
-
-
-
-
-
4
2
-
2
-
-
-
-
-
4
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641198
Gallais
-
Changes in soluble and membran ...
Avena sativa
Aust. J. Plant Physiol.
27
649-658
2000
1
1
-
-
-
-
-
-
2
1
-
1
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
1
1
-
1
-
-
-
-
-
-
-
2
1
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641188
Delumeau
-
Effect of aluminum on the NAD+ ...
Euglena gracilis, Euglena gracilis Z
Biol. Plant.
41
415-425
1998
-
-
-
-
-
-
-
-
-
-
-
2
-
21
-
-
-
-
-
1
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641195
Morere-Le Paven
-
NAD+ kinase activities in Eugl ...
Euglena gracilis, Euglena gracilis Z, Phaseolus vulgaris
Biol. Plant.
40
565-574
1998
-
-
-
-
-
-
-
-
-
-
-
-
-
22
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641199
Delumeau
-
NAD+ kinase activity, calmodul ...
Solanum pimpinellifolium
Plant Sci.
138
43-52
1998
1
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
1
1
-
2
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
1
-
2
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641194
Guerrier
-
Proline metabolism and NAD kin ...
Glycine max
Biol. Plant.
40
1-9
1997
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
641196
Lee
Differential activation of NAD ...
Pisum sativum
J. Biol. Chem.
272
9252-9259
1997
1
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
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641190
Liao
Differential stimulation of NA ...
Pisum sativum
Arch. Biochem. Biophys.
327
53-60
1996
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641183
Zerez
NAD kinase from Bacillus liche ...
Bacillus licheniformis
Arch. Microbiol.
144
313-316
1986
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641201
Williams
Calmodulin-dependent NAD kinas ...
Homo sapiens
Arch. Biochem. Biophys.
237
80-87
1985
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641202
McGuiness
NAD+ kinase-a review ...
Achromobacter aceris, Azotobacter vinelandii, Bos taurus, Columba sp., Corynebacterium ammoniagenes, Cyberlindnera jadinii, Gallus gallus, Homo sapiens, Nicotiana tabacum, Oryctolagus cuniculus, Pisum sativum, Rattus norvegicus, Saccharomyces cerevisiae, Spinacia oleracea, Triatoma infestans
Int. J. Biochem.
17
1-11
1985
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20
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9
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8
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641181
Ji
Immobilization of NAD kinase ...
Gallus gallus
Ann. N. Y. Acad. Sci.
434
264-266
1984
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641200
Muto
-
Kinetic nature of calmodulin-d ...
Pisum sativum
Z. Pflanzenphysiol.
109
385-393
1983
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7
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641176
Butler
Candida utilis NAD+ kinase: pu ...
Cyberlindnera jadinii
Int. J. Biochem.
14
839-844
1982
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641178
Bulygina
-
Properties of pigeon heart nic ...
Columba sp.
Biochem. Int.
4
135-141
1982
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641179
Blomquist
NAD+ kinase from sea urchin eg ...
Strongylocentrotus purpuratus
Methods Enzymol.
66
101-104
1980
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641185
Tseng
Isolation and characterization ...
Saccharomyces cerevisiae
Biochim. Biophys. Acta
568
205-214
1979
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641182
Apps
Pigeon-liver NAD kinase. The s ...
Columba sp.
Eur. J. Biochem.
55
475-483
1975
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641180
Blomquist
Partial purification and chara ...
Strongylocentrotus purpuratus
J. Biol. Chem.
248
7044-7048
1973
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641184
Orringer
Nicotinamide adenine dinucleot ...
Azotobacter vinelandii
Biochim. Biophys. Acta
250
86-91
1971
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2
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641177
Chung
Nicotinamide adenine dinucleot ...
Azotobacter vinelandii
J. Biol. Chem.
242
1182-1186
1967
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