Literature summary for 2.7.1.220 extracted from

Zhang, X.; Carter, M.; Vetting, M.; Francisco, B.; Zhao, S.; Al-Obaidi, N.; Solbiati, J.; Thiaville, J.; Crecy-Lagard, V.; Jacobson, M.; Almo, S.; Gerlt, J.
Assignment of function to a domain of unknown function DUF1537 is a new kinase family in catabolic pathways for acid sugars (2016), Proc. Natl. Acad. Sci. USA, 113, E4161-E4169 .

Search for more literature for 2.7.1.220

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.081	-	D-erythronate	pH 8.0, 25°C	Heliomicrobium modesticaldum
3.2	-	D-threonate	pH 8.0, 25°C	Heliomicrobium modesticaldum
44	-	4-hydroxy-L-threonine	pH 8.0, 25°C	Heliomicrobium modesticaldum

Organism

Organism	UniProt	Comment	Textmining
Heliomicrobium modesticaldum	B0TBI9	-	-
Heliomicrobium modesticaldum ATCC 51547	B0TBI9	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 4-hydroxy-L-threonine	-	Heliomicrobium modesticaldum	ADP + 4-phospho-L-threonine	-	?
ATP + 4-hydroxy-L-threonine	-	Heliomicrobium modesticaldum ATCC 51547	ADP + 4-phospho-L-threonine	-	?
ATP + D-erythronate	-	Heliomicrobium modesticaldum	ADP + 4-phospho-D-erythronate	-	?
ATP + D-erythronate	-	Heliomicrobium modesticaldum ATCC 51547	ADP + 4-phospho-D-erythronate	-	?
ATP + D-threonate	-	Heliomicrobium modesticaldum	ADP + 4-phospho-D-threonate	-	?
ATP + D-threonate	-	Heliomicrobium modesticaldum ATCC 51547	ADP + 4-phospho-D-threonate	-	?

Synonyms

Synonyms	Comment	Organism
denK	-	Heliomicrobium modesticaldum

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
12	-	D-threonate	pH 8.0, 25°C	Heliomicrobium modesticaldum
16	-	D-erythronate	pH 8.0, 25°C	Heliomicrobium modesticaldum
41	-	4-hydroxy-L-threonine	pH 8.0, 25°C	Heliomicrobium modesticaldum

kcat/KM [mM/s]

kcat/KM Value [1/mMs^-1]	kcat/KM Value Maximum [1/mMs^-1]	Substrate	Comment	Organism	Structure
0.94	-	4-hydroxy-L-threonine	pH 8.0, 25°C	Heliomicrobium modesticaldum
3.8	-	D-threonate	pH 8.0, 25°C	Heliomicrobium modesticaldum
190	-	D-erythronate	pH 8.0, 25°C	Heliomicrobium modesticaldum

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)