Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | bisubstrate analogs with adenosine and thymidine joined at their 5' positions by polyphorphoryl linkages of varying lengths can serve as inhibitors | Homo sapiens | |
P1-(Adenosine-5')-P3-(thymidine-5')-triphosphate | - |
Homo sapiens | |
P1-(adenosine-5')-P4-(thymidine-5')-tetraphosphate | - |
Homo sapiens | |
P1-(Adenosine-5')-P5-(thymidine-5')-pentaphosphate | - |
Homo sapiens | |
P1-(Adenosine-5')-P6-(thymidine-5')-hexaphosphate | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0026 | - |
thymidine | mitochondrial enzyme, pH 7.5, 37°C | Homo sapiens | |
0.01 | - |
thymidine | cytosolic enzyme, pH 7.5, 37°C | Homo sapiens | |
0.07 | - |
ATP | cytosolic enzyme, pH 7.5, 37°C | Homo sapiens | |
0.11 | - |
ATP | mitochondrial enzyme, pH 7.5, 37°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blast cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + thymidine | - |
Homo sapiens | ADP + dTMP | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | bisubstrate analogs with adenosine and thymidine joined at their 5' positions by polyphorphoryl linkages of varying lengths | Homo sapiens |