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Literature summary for 2.7.1.20 extracted from

  • Romanello, L.; Bachega, J.F.; Cassago, A.; Brandao-Neto, J.; DeMarco, R.; Garratt, R.C.; Pereira, H.D.
    Adenosine kinase from Schistosoma mansoni: structural basis for the differential incorporation of nucleoside analogues (2013), Acta Crystallogr. Sect. D, 69, 126-136.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Schistosoma mansoni

Crystallization (Commentary)

Crystallization (Comment) Organism
in complex with N6,N6-dimethyladenosine, beta,gamma-methyleneadenosine 5’-triphosphate, and 6-methyl mercaptopurine riboside, hanging drop vapor diffusion method, using 19-21% (w/v) PEG 4000, 0.2 M ammonium acetate, 0.1 M sodium citrate pH 6.0-6.5 Schistosoma mansoni

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + adenosine Schistosoma mansoni
-
ADP + AMP
-
?

Organism

Organism UniProt Comment Textmining
Schistosoma mansoni
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Econo-Pac 10DG column chromatography Schistosoma mansoni

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + adenosine
-
Schistosoma mansoni ADP + AMP
-
?

Synonyms

Synonyms Comment Organism
ADK
-
Schistosoma mansoni