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Literature summary for 2.7.1.20 extracted from

  • Boison, D.
    The adenosine kinase hypothesis of epileptogenesis (2008), Prog. Neurobiol., 84, 249-262.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine ADK has emerged as a novel target to predict and to prevent epileptogenesis. High levels of ADK expression (e.g. as a long-term consequence of traumatic brain injury) are expected to be predictive for subsequent epileptogenesis. This means that the determination of ADK expression levels in brain, e.g. by using ADK-selective PET or SPECT ligands, has high diagnostic value. On the other hand, prevention of epileptogenesis by focal reconstitution of the adenosine system is an important therapeutic goal Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
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Synonyms

Synonyms Comment Organism
ADK
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Homo sapiens