Cloned (Comment) | Organism |
---|---|
- |
Mycobacterium tuberculosis |
Crystallization (Comment) | Organism |
---|---|
crystals are obtained by either hanging drop or sitting drop vapor diffusion methods. Crystal structure of of ADK unliganded as well as ligand (adenosine) bound at 1.5- and 1.9-A resolution, respectively. The structure of the binary complexes with the inhibitor 2-fluoroadenosine bound and with the adenosine 5'-(beta,gamma-methylene)triphosphate (non-hydrolyzable ATP analog) bound are solved at 1.9-A resolution | Mycobacterium tuberculosis |
hanging drop or sitting drop vapor diffusion methods. Crystal structure of unliganded enzyme as well as adenosine bound enzyme at 1.5 A and 1.9 A resolution, respectively. The structure of the binary complexes with the inhibitor 2-fluoroadenosine bound and with the adenosine 5'-(beta,gamma-methylene)triphosphate bound are solved at 1.9 A resolution | Mycobacterium tuberculosis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + adenosine | Mycobacterium tuberculosis | - |
ADP + AMP | - |
? | |
ATP + adenosine | Mycobacterium tuberculosis H37Rv | - |
ADP + AMP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Mycobacterium tuberculosis | P9WID5 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WID5 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + adenosine | - |
Mycobacterium tuberculosis | ADP + AMP | - |
? | |
ATP + adenosine | - |
Mycobacterium tuberculosis H37Rv | ADP + AMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADK | - |
Mycobacterium tuberculosis |