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Literature summary for 2.7.1.190 extracted from

  • Ferretti, J.; Gilmore, K.; Courvalin, P.
    Nucleotide sequence analysis of the gene specifying the bifunctional 6-aminoglycoside acetyltransferase 2-aminoglycoside phosphotransferase enzyme in Streptococcus faecalis and identification and cloning of gene regions specifying the two activities (1986), J. Bacteriol., 167, 631-638.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Enterococcus faecalis

Protein Variants

Protein Variants Comment Organism
additional information The N-terminal region contains a sequence homologous to the chloramphenicol acetyltransferase of Bacillus pumUus, and the C-terminal region contains a sequence homologous to the aminoglycoside phosphotransferase of Streptomyces fradiae. It is possible to obtain gene segments independently specifying the acetyltransferase and phosphotransferase activities Enterococcus faecalis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56000
-
x * 56000, SDS-PAGE, x * 56850, calculated Enterococcus faecalis
56850
-
x * 56000, SDS-PAGE, x * 56850, calculated Enterococcus faecalis

Organism

Organism UniProt Comment Textmining
Enterococcus faecalis P0A0C2
-
-
Enterococcus faecalis ATCC 700802 P0A0C2
-
-

Subunits

Subunits Comment Organism
? x * 56000, SDS-PAGE, x * 56850, calculated Enterococcus faecalis

Synonyms

Synonyms Comment Organism
aacA-aphD
-
Enterococcus faecalis
bifunctional 6'-aminoglycoside acetyltransferase/2"-aminoglycoside phosphotransferase
-
Enterococcus faecalis
bifunctional AAC/APH
-
Enterococcus faecalis