Protein Variants | Comment | Organism |
---|---|---|
D264E | loss of activity | Escherichia coli |
D264N | loss of enzymatic activity in the mutant protein is not caused by drastic alterations in protein structure | Escherichia coli |
E198D | loss of enzymatic activity in the mutant protein is not caused by drastic alterations in protein structure | Escherichia coli |
N195D | loss of activity | Escherichia coli |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
83000 | - |
gel filtration | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P76658 | bifunctional protein hldE includes: D-beta-D-heptose 7-phosphate kinase and D-beta-D-heptose 1-phosphate adenosyltransferase | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glycero-D-manno-heptose 7-phosphate + ATP | - |
Escherichia coli | D-glycero-beta-D-manno-heptose 1,7-bisphosphate + ADP | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | HldE comprises two functional domains: an N-terminal region with homology to the ribokinase superfamily (HldE1 domain) and a C-terminal region with homology to the cytidylyltransferase superfamily. HldE functional unit is a dimer and structural components present in each HldE1 monomer are required for enzymatic activity | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
D-beta-D-heptose 7-phosphotransferase | - |
Escherichia coli |
D-beta-D-heptose-7-phosphate kinase | - |
Escherichia coli |
glycero-manno-heptose 7-phosphate kinase | - |
Escherichia coli |
heptose 7-phosphate kinase | - |
Escherichia coli |
HldE1 heptokinase | - |
Escherichia coli |