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BRENDA support

Literature summary for 2.7.1.153 extracted from

  • Turner, S.J.; Domin, J.; Waterfield, M.D.; Ward, S.G.; Westwick, J.
    The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha (1998), J. Biol. Chem., 273, 25987-25995.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
monocyte chemotactic peptide-1 i.e. MCP-1, stimulation can be inhibited by pertussis toxin, but not by wortmannin Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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isoform p85/p110 phosphatidylinositol 3-kinase
-

Source Tissue

Source Tissue Comment Organism Textmining
THP-1 cell monocytic cell line Homo sapiens
-