Literature summary for 2.7.1.153 extracted from

Stirdivant, S.M.; Ahern, J.; Conroy, R.R.; Barnett, S.F.; Ledder, L.M.; Oliff, A.; Heimbrook, D.C.
Cloning and mutagenesis of the p110 alpha subunit of human phosphoinositide 3'-hydroxykinase (1997), Bioorg. Med. Chem., 5, 65-74.

Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Protein Variants	Comment	Organism
D915A	complete loss of enzymic activity	Homo sapiens
D933A/F934A	complete loss of enzymic activity	Homo sapiens
E970A	90% of wild-type activity	Homo sapiens
R922A	80% of wild-type activity	Homo sapiens

Organism	UniProt	Comment	Textmining
Homo sapiens	P42336	catalytic subunit p110, alpha isoform	-

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Release 2023.1 (January 2023)