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Literature summary for 2.7.1.15 extracted from

  • Riggs, J.W.; Rockwell, N.C.; Cavales, P.C.; Callis, J.
    Identification of the plant ribokinase and discovery of a role for Arabidopsis ribokinase in nucleoside metabolism (2016), J. Biol. Chem., 291, 22572-22582 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.15

Inhibitors

Inhibitors Comment Organism Structure
ATP substrate inhibition Arabidopsis thaliana

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.045
-
 ATP pH 8.0, temperature not specified in the publication Arabidopsis thaliana
0.15
-
 D-ribose pH 8.0, temperature not specified in the publication Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + D-ribose Arabidopsis thaliana
-
 ADP + D-ribose 5-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana A1A6H3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + D-ribose
-
 Arabidopsis thaliana ADP + D-ribose 5-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
At1g17160
-
 Arabidopsis thaliana
RBSK
-
 Arabidopsis thaliana

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2
-
 ATP pH 8.0, temperature not specified in the publication Arabidopsis thaliana
2
-
 D-ribose pH 8.0, temperature not specified in the publication Arabidopsis thaliana

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.44
-
 ATP pH 8.0, temperature not specified in the publication Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction Arabidopsis plants lacking the enzyme (AtRBSK) grow normally unless media is supplemented with ribose, which led to chlorosis and growth inhibition. The loss of protein is responsible for ribose hypersensitivity Arabidopsis thaliana