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Literature summary for 2.7.1.149 extracted from

  • Elouarrat, D.; van der Velden, Y.U.; Jones, D.R.; Moolenaar, W.H.; Divecha, N.; Haramis, A.P.
    Role of phosphatidylinositol 5-phosphate 4-kinase ? in zebrafish development (2013), Int. J. Biochem. Cell Biol., 45, 1293-1301.
    View publication on PubMed
Search for more literature for 2.7.1.149

Cloned(Commentary)

Cloned (Comment) Organism
-
 Danio rerio

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
46000
-
 x * 46000, SDS-PAGE Danio rerio

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate Danio rerio
-
 ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Danio rerio
-
-
-

Purification (Commentary)

Purification (Comment) Organism
heparin agarose column chromatography Danio rerio

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Danio rerio
-
central nervous system
-
 Danio rerio
-
embryo
-
 Danio rerio
-
eye
-
 Danio rerio
-
fin
-
 Danio rerio
-
retina
-
 Danio rerio
-
somite
-
 Danio rerio
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate
-
 Danio rerio ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 46000, SDS-PAGE Danio rerio

Synonyms

Synonyms Comment Organism
phosphatidylinositol 5-phosphate 4-kinase
-
 Danio rerio
PIP4Kalpha
-
 Danio rerio

Expression

Organism Comment Expression
Danio rerio at later embryonic stages, high PIP4Kalpha expression is detected in the head and the pectoral fins up

General Information

General Information Comment Organism
malfunction enzyme knockdown leads to severe morphological abnormalities, including midbody winding defects at 48 h post-fertilization Danio rerio