Application | Comment | Organism |
---|---|---|
medicine | potentially important therapeutic target in oncology and inflammation | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression in baculovirus-infected SF9 insect cells | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.031 | - |
ATP | - |
Homo sapiens | |
0.107 | - |
C12-ceramide | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ceramide + ATP | Homo sapiens | ceramide is a key mediator of cellular apoptosis | ceramide 1-phosphate + ADP | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
nickel-nitriloacetate resin chromatography | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
C12-ceramide + ATP | - |
Homo sapiens | C12-ceramide 1-phosphate + ADP | - |
? | |
ceramide + ATP | - |
Homo sapiens | ceramide 1-phosphate + ADP | - |
? | |
ceramide + ATP | ceramide is a key mediator of cellular apoptosis | Homo sapiens | ceramide 1-phosphate + ADP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CERK | - |
Homo sapiens |