KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.004 | - |
stearoylceramide | pH 7.4, 30°C, without Ca2+ | Rattus norvegicus | |
0.009 | - |
stearoylceramide | pH 7.4, 30°, in the presence of 0.010 mM Ca2+ | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
synaptic vesicle membrane | - |
Rattus norvegicus | 30672 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | 0.0001-0.0005 mM, 15-20fold increase in activity, 0.0005 mM, 60fold stimulation | Rattus norvegicus | |
Mg2+ | millimolar concentrations, 20fold stimulation | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + ceramide | Rattus norvegicus | ceramide phosphorylation may be associated with neurotransmitter release | ADP + ceramide 1-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + ceramide | other name n-acyl-sphingosine, no activity with CTP, CDPcholine and UDPglucose | Rattus norvegicus | ADP + ceramide 1-phosphate | - |
? | |
ATP + ceramide | ceramide phosphorylation may be associated with neurotransmitter release | Rattus norvegicus | ADP + ceramide 1-phosphate | - |
? | |
ATP + stearoylceramide | - |
Rattus norvegicus | ADP + stearoylceramide 1-phosphate | - |
? | |
GTP + ceramide | 26% of the activity with ATP at 1 mM | Rattus norvegicus | GDP + ceramide 1-phosphate | - |
? |