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Literature summary for 2.7.1.127 extracted from

  • Stokes, A.J.; Shimoda, L.M.; Lee, J.W.; Rillero, C.; Chang, Y.; Turner, H.
    FceRI control of Ras via inositol (1,4,5) trisphosphate 3-kinase and inositol tetrakisphosphate (2006), Cell. Signal., 18, 640-651.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1D-myo-inositol 1,4,5-trisphosphate Rattus norvegicus InsP3K activity is a determinant of the extent of basal Ras activation in mast cells and of the Ras activation that follows antigenic crosslinking of the FcepsilonRI ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
RBL-2H3 cell mast cell Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1D-myo-inositol 1,4,5-trisphosphate
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Rattus norvegicus ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
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?
ATP + 1D-myo-inositol 1,4,5-trisphosphate InsP3K activity is a determinant of the extent of basal Ras activation in mast cells and of the Ras activation that follows antigenic crosslinking of the FcepsilonRI Rattus norvegicus ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
-
?

Synonyms

Synonyms Comment Organism
inositol (1,4,5) trisphosphate 3-kinase
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Rattus norvegicus
InsP3K
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Rattus norvegicus