Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | ATP protects | Sus scrofa | |
Mg2+ | at each level of ATP the optimal molar concentration of Mg2+ is one-half that of ATP, higher concentration inhibits | Sus scrofa | |
additional information | not: iodoacetate | Sus scrofa | |
NaF | not | Sus scrofa | |
p-chloromercuribenzoate | - |
Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | can partially replace Mg2+ in activation | Sus scrofa | |
Co2+ | can partially replace Mg2+ in activation | Sus scrofa | |
Mg2+ | activates | Sus scrofa | |
Mg2+ | at each level of ATP the optimal molar concentration of Mg2+ is one-half that of ATP, higher concentration inhibits | Sus scrofa | |
Mn2+ | can partially replace Mg2+ in activation | Sus scrofa | |
Zn2+ | can partially replace Mg2+ in activation | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-gluconate | Sus scrofa | - |
ADP + 6-phospho-D-gluconate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.64 | - |
- |
Sus scrofa |
Storage Stability | Organism |
---|---|
-15°C, 10% loss of activity after 3 weeks | Sus scrofa |
3°C, 50% loss of activity after 3 weeks | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-gluconate | - |
Sus scrofa | ADP + 6-phospho-D-gluconate | - |
? | |
ATP + D-gluconate | strict specificity for D-gluconate | Sus scrofa | ADP + 6-phospho-D-gluconate | - |
? | |
GTP + D-gluconate | 25% of the activity with ATP | Sus scrofa | GDP + 6-phospho-D-gluconate | - |
? | |
ITP + D-gluconate | 60% of the activity with ATP | Sus scrofa | IDP + 6-phospho-D-gluconate | - |
? | |
UTP + D-gluconate | 130% of the activity with ATP | Sus scrofa | UDP + 6-phospho-D-gluconate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
34 | - |
assay at | Sus scrofa |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.2 | - |
- |
Sus scrofa |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.1 | 8.4 | pH 5.1: about 25% of activity maximum, pH 8.4: about 50% of activity maximum | Sus scrofa |