Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose 6-phosphate | Mus musculus | phosphofructokinase-1 is an important control point in the glycolytic pathway, it is implicated in the functions of astrocytes and neurons | ADP + D-fructose 1,6-bisphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neural stem cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose 6-phosphate | - |
Mus musculus | ADP + D-fructose 1,6-bisphosphate | - |
? | |
ATP + D-fructose 6-phosphate | phosphofructokinase-1 is an important control point in the glycolytic pathway, it is implicated in the functions of astrocytes and neurons | Mus musculus | ADP + D-fructose 1,6-bisphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PFK-1 | - |
Mus musculus |
phosphofructokinase-1 | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | knockdown of phosphofructokinase-1 promotes neurogenesis by enhancing the proliferation of neural progenitors and instructing these progenitors to adopt a neuronal fate, and this effect is achieved by the upregulation of Mash 1, NeuroD, and Sox2 | Mus musculus |
physiological function | phosphofructokinase-1 is an important regulator of neurogenesis | Mus musculus |