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Literature summary for 2.7.1.11 extracted from
- Enhanced butanol production in Clostridium acetobutylicum ATCC 824 by double overexpression of 6-phosphofructokinase and pyruvate kinase genes (2013), Appl. Microbiol. Biotechnol., 97, 7505-7516.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | overexpression of both the 6-phosphofructokinase pfkA and pyruvate kinase pykA genes increase intracellular concentrations of ATP and NADH and also resistance to butanol toxicity. Marked increases of butanol and ethanol production, but not acetone, are observed in batch fermentation. The butanol and ethanol concentrations are 29.4 and 85.5% higher, respectively, in the fermentation by the double-overexpressing strain than the wild-type strain. In fed-batch fermentation using glucose, the butanol and total solvent (acetone, butanol, and ethanol) concentrations reach as high as 19.12 and 28.02 g/l, respectively | Clostridium acetobutylicum |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Clostridium acetobutylicum |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium acetobutylicum | O08308 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PFKA | - |
Clostridium acetobutylicum |
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