Literature summary for 2.7.1.11 extracted from

Kemp, R.G.; Gunasekera, D.
Evolution of the allosteric ligand sites of mammalian phosphofructo-1-kinase (2002), Biochemistry, 41, 9426-9430.

Protein Variants

Protein Variants	Comment	Organism
R429A	no change in Km for ATP and fructose 6-phosphate, less sensitive to inhibition by ATP	Mus musculus
R433A	no change in Km for ATP and fructose 6-phosphate, not inhibited by ATP up to 6 mM, Arg433 is probably a component of the inhibitory site for ATP	Mus musculus

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

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Release 2023.1 (January 2023)