Literature summary for 2.7.1.11 extracted from

Yaney, G.C.; Schultz, V.; Cunningham, B.A.; Dunaway, G.A.; Corkey, B.E.; Tornheim, K.
Phosphofructokinase isozymes in pancreatic islets and clonal beta-cells (INS-1) (1995), Diabetes, 44, 1285-1289.

Search for more literature for 2.7.1.11

Activating Compound

Activating Compound	Comment	Organism	Structure
D-fructose 1,6-bisphosphate	activation of PFK in INS-1 cell extract	Rattus norvegicus
D-fructose 2,6-bisphosphate	activation of PFK in INS-1 cell extract	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
citrate	inhibition of M- and C-type PFK in pancreatic beta-cells	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	M-type, i.e. muscle-type, C-type, i.e. fibroplast-type, and L-type, i.e. liver-type, PFK isoforms	Rattus norvegicus	-
pancreatic beta cell line	INS-1 cells, M-type, i.e. muscle-type, C-type, i.e. fibroplast-type, and perhaps lesser amounts of L-type, i.e. liver-type, PFK isoforms	Rattus norvegicus	-
pancreatic islet	M-type, i.e. muscle-type, C-type, i.e. fibroplast-type, and perhaps lesser amounts of L-type, i.e. liver-type, PFK isoforms	Rattus norvegicus	-
skeletal muscle	only M-type, i.e. muscle-type PFK isoenzyme	Rattus norvegicus	-

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Release 2023.1 (January 2023)