Activating Compound | Comment | Organism | Structure |
---|---|---|---|
(R)-dolichol (C95) | markedly stimulated by addition, Km 0.009 mM | Bos taurus | |
(S)-dolichol (C95) | markedly stimulated by addition, Km 0.009 mM | Bos taurus | |
phosphatidylcholine | stimulated by after dialysis | Bos taurus | |
phosphatidylethanolamine | stimulated by after dialysis | Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
CDP | - |
Bos taurus | |
dCDP | - |
Bos taurus | |
EDTA | - |
Bos taurus | |
additional information | not inhibited by CMP, ADP, GDP or UDP | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0077 | - |
CTP | pH 7.2, 37°C | Bos taurus | |
0.0091 | - |
dCTP | pH 7.2, 37°C | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Bos taurus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Bos taurus | |
Zn2+ | markedly stimulated by | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + dolichol | Bos taurus | - |
CDP + dolichyl phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
calf | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Bos taurus | - |
Storage Stability | Organism |
---|---|
-17°C, 65% of original activity retains when stored for 6 weeks | Bos taurus |
4°C, no detectable loss of activity when solubilized extract is kept for 24 h | Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + dolichol | - |
Bos taurus | CDP + dolichyl phosphate | - |
? | |
dCTP + dolichol | - |
Bos taurus | dCDP + dolichyl phosphate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Bos taurus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.121 | - |
CDP | pH 7.2, 37°C | Bos taurus |