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Literature summary for 2.7.1.107 extracted from

  • Hayashi, D.; Wang, L.; Ueda, S.; Yamanoue, M.; Ashida, H.; Shirai, Y.
    The mechanisms of ameliorating effect of a green tea polyphenol on diabetic nephropathy based on diacylglycerol kinase alpha (2020), Sci. Rep., 10, 11790 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.107

Activating Compound

Activating Compound Comment Organism Structure
epigallocatechin gallate
-
 Mus musculus

Application

Application Comment Organism
medicine isoform DGKalpha can be used as strategy for treating diabetic nephropathy Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1,2-diacyl-sn-glycerol Mus musculus
-
 ADP + 1,2-diacyl-sn-glycerol 3-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus O88673
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1,2-diacyl-sn-glycerol
-
 Mus musculus ADP + 1,2-diacyl-sn-glycerol 3-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
DGKalpha isoform Mus musculus
diacylglycerol kinase alpha isoform Mus musculus

General Information

General Information Comment Organism
physiological function isoform DGKalpha plays a crucial role in the amelioration of diabetic nephropathy and contributes to the effect of epigallocatechin gallate on diabetic nephropathy Mus musculus