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Literature summary for 2.7.1.105 extracted from

  • Bao, J.; Wu, Y.; Wang, L.; Zhu, Y.
    The role of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 in esophageal squamous cell carcinoma (2020), Medicine (Baltimore), 99, e19626 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.1.105

Application

Application Comment Organism
medicine high PFKFB3 protein and gene expression may be associated with the occurrence, development, and prognosis of esophageal squamous cell carcinoma Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + beta-D-fructose 6-phosphate Homo sapiens
-
 ADP + beta-D-fructose 2,6-bisphosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q16875
-
-

Source Tissue

Source Tissue Comment Organism Textmining
esophageal squamous cell carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + beta-D-fructose 6-phosphate
-
 Homo sapiens ADP + beta-D-fructose 2,6-bisphosphate
-
 ?

Synonyms

Synonyms Comment Organism
6-phosphofructo kinase-2/fructose diphosphatase-2 isoenzyme 3
-
 Homo sapiens
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3
-
 Homo sapiens
PFKFB3
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens enzyme expression in esophageal squamous cell carcinoma cell is significantly higher than in adjacent non-tumor tissues up